Evidence map›Paper›PMID 31180051›Full record

ReviewJournal of biosciences2019

Restriction enzymes and their use in molecular biology: An overview.

Francesca DI Felice, Gioacchino Micheli, Giorgio Camilloni

Abstract readHistorical ArticleReview
PubMed
In one paragraph

Review in Journal of biosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  6. Review
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  13. Review
  14. Genetic Markers in Lung Cancer Diagnosis: A Review.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francesca DI FeliceDipartimento di Biologia e Biotecnologie, Sapienza, Universita di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
Gioacchino Micheli
Giorgio Camilloni

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Restriction enzymes have been identified in the early 1950s of the past century and have quickly become key players in the molecular biology of DNA. Forty years ago, the scientists whose pioneering work had explored the activity and sequence specificity of these enzymes, contributing to the definition of their enormous potential as tools for DNA characterization, mapping and manipulation, were awarded the Nobel Prize. In this short review, we celebrate the history of these enzymes in the light of their many different uses, as these proteins have accompanied the history of DNA for over 50 years representing active witnesses of major steps in the field.

Indexed as

ChromatinChromosome MappingCloning, MolecularCRISPR-Cas SystemsDNADNA MethylationDNA Restriction EnzymesHistory, 20th CenturyHistory, 21st CenturyHumansMolecular BiologyNobel PrizeNucleotide MappingTranscription Activator-Like Effector NucleasesChromatinDNADNA Restriction EnzymesTranscription Activator-Like Effector Nucleases

Identifiers

PMID31180051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.