Evidence map›Paper›PMID 31179788›Full record

ArticleThe Journal of international medical research2019

Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway.

Xue-Wu Xing, Yu-Fu Sun, Jun Zhao, Zi-Xiang Pan, Wen-Xue Jiang

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Comparative Study of the Antiemetic Effects of αInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. C₁₈H₁₇NO₆ Inhibits Invasion and Migration of Human MNNG Osteosarcoma Cells via the PI3K/AKT Signaling Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xue-Wu Xing1 Department of Orthopedics, Tianjin First Central Hospital, Tianjin, P.R. China.
Yu-Fu Sun1 Department of Orthopedics, Tianjin First Central Hospital, Tianjin, P.R. China.
Jun Zhao2 Department of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute & Hospital, Tianjin, P.R. China.
Zi-Xiang Pan1 Department of Orthopedics, Tianjin First Central Hospital, Tianjin, P.R. China.
Wen-Xue Jiang1 Department of Orthopedics, Tianjin First Central Hospital, Tianjin, P.R. China.ORCID https://orcid.org/0000-0003-4478-7944
Tianjin First Center Hospital · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnticonvulsantsBone NeoplasmsCell MovementCell ProliferationClonidineGene Expression Regulation, NeoplasticHumansOsteosarcomaPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionTumor Cells, CulturedAnticonvulsantsClonidinePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akttizanidinemigrationosteosarcomaPI3K/AKTproliferationTizanidine hydrochlorideα2-adrenergic receptor

Identifiers

PMID31179788
PMCPMC6726809
OpenAlexW2950741499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.