Evidence map›Paper›PMID 31179241›Full record

ArticleFrontiers in oncology2019

TIPE1 Inhibits Breast Cancer Proliferation by Downregulating ERK Phosphorylation and Predicts a Favorable Prognosis.

Wei Hu, Chun-Mei Feng, Ling-Yun Liu, Na Li, Feng Tian, Jian-Xin Du, Yi Zhao, Xin-Xin Xiang, Kui Liu, Pei-Qing Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Open life sciences · 2022
    Article
  6. Understanding the regulation of β-catenin expression and activity in colorectal cancer carcinogenesis: beyond destruction complex.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wei HuDepartment of Breast and Thyroid Surgery, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
Chun-Mei FengZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Ling-Yun LiuZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Na LiZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Feng TianZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Jian-Xin DuZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Yi ZhaoSchool of Stomatology, Shandong University, Jinan, China.
Xin-Xin XiangZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Kui LiuZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Pei-Qing ZhaoZibo Central Hospital Affiliated to Shandong University, Center of Translational Medicine, Zibo, China.
Central Hospital of Zibo · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TIPE1, which acts as a cell death regulator, has emerged as a tumor suppressor in the process of carcinogenesis. However, our recent research demonstrated that it serves as an oncogene in the pathogenesis of cervical cancer, indicating that the role of TIPE1 in carcinogenesis needs to be further evaluated. In this study, we show that TIPE1 is able to inhibit breast cancer cell growth both

Indexed as

breast cancerERKprognosisproliferationTIPE1

Identifiers

PMID31179241
PMCPMC6538679
OpenAlexW2944686486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.