Evidence map›Paper›PMID 31179221›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019

Anisotropic Plasmonic Metal Heterostructures as Theranostic Nanosystems for Near Infrared Light-Activated Fluorescence Amplification and Phototherapy.

Yun Chang, Yanlin Feng, Yan Cheng, Runxiao Zheng, Xiaqing Wu, Hui Jian, Dawei Zhang, Zhaohui Tang, Zhenxin Wang, Jiaming Hao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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  6. Engineering biocompatible TeSeNational science review · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yun ChangLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.ORCID https://orcid.org/0000-0003-0731-7943
Yanlin FengLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Yan ChengLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Runxiao ZhengLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Xiaqing WuLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Hui JianLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Dawei ZhangKey Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Zhaohui TangKey Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Zhenxin WangState Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Jiaming HaoState Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences Shanghai 200083 China.
Haiyuan ZhangLaboratory of Chemical Biology Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China.
Chinese Academy of Sciences · CNUniversity of Science and Technology of China · CNShanghai Institute of Technical Physics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of sophisticated theranostic systems for simultaneous near infrared (NIR) fluorescence imaging and phototherapy is of particular interest. Herein, anisotropic plasmonic metal heterostructures, Pt end-deposited Au nanorods (PEA NRs), are developed to efficiently produce hot electrons under 808 nm laser irradiation, exhibiting the strong electric density. These hot electrons can release the heat through electron-phonon relaxation and form reactive oxygen species through chemical transformation, as a result of potent photothermal and photodynamic performance. Simultaneously, the confined electromagnetic field of PEA NRs can transfer energy to adjacent polyethylene glycol (PEG)-linked NIR fluorophores (CF) based on their energy overlap mechanism, leading to remarkable NIR fluorescence amplification in CF-PEA NRs. Various PEG linkers (1, 3.4, 5.0, and 10 kD) are employed to regulate the distance between CF and PEA NRs of CF-PEA NRs, and the maximum fluorescence intensity is achieved in CF

Indexed as

anisotropic heterostructuresfluorescence amplificationhot electronsphototherapytheranostics

Identifiers

PMID31179221
PMCPMC6548947
OpenAlexW2931955445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.