ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019
Definition of a Family of Nonmobile Colistin Resistance (NMCR-1) Determinants Suggests Aquatic Reservoirs for MCR-4.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Genomic analysis of MCR-8 and NDM-5 coproducingBiosafety and health · 2026Article
- Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Silent Threat Evolution: Critically Important Carbapenem and Colistin Resistance Genes in the Natural Aquatic Environment.Antibiotics (Basel, Switzerland) · 2026Review
- Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump.Nature communications · 2025Article
- A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway.Science advances · 2024Article
- Sequence variation in the active site of mobile colistin resistance proteins is evolutionarily accommodated through inter-domain interactions.The Biochemical journal · 2024Article
- Review
- Comparative genome analysis of the genusFrontiers in microbiology · 2023Article
- Novel Plasmid Carrying Mobile Colistin Resistance GeneMicrobiology spectrum · 2022Article
- Review
- Dissemination of Carbapenemases and MCR-1 Producing Gram-Negative Bacteria in Aquatic Environments in Batna, Algeria.Antibiotics (Basel, Switzerland) · 2022Article
- Prevalence and characteristics of the mcr-1 gene in retail meat samples in Zhejiang Province, China.Journal of microbiology (Seoul, Korea) · 2022Article
- Re-sensitization ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Genomic analysis reveals high intra-species diversity ofMicrobial genomics · 2022Article
- Global epidemiology, genetic environment, risk factors and therapeutic prospects ofFrontiers in cellular and infection microbiology · 2022Review
- The variants of polymyxin susceptibility in different species of genusFrontiers in microbiology · 2022Article
- New insights about the EptA protein and its correlation with theCurrent research in microbial sciences · 2021Article
- Recent progress on elucidating the molecular mechanism of plasmid-mediated colistin resistance and drug design.International microbiology : the official journal of the Spanish Society for Microbiology · 2020Review
- Massive analysis of 64,628 bacterial genomes to decipher water reservoir and origin of mobile colistin resistance genes: is there another role for these enzymes?Scientific reports · 2020Article
- Occurrence and Characteristics of Mobile Colistin Resistance (International journal of environmental research and public health · 2020Review
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymyxins, a family of cationic antimicrobial peptides, are recognized as a last-resort clinical option used in the treatment of lethal infections with carbapenem-resistant pathogens. A growing body of mobile colistin resistance (MCR) determinants renders colistin ineffective in the clinical and human sectors, posing a challenge to human health and food security. However, the origin and reservoir of the MCR family enzymes is poorly understood. Herein, a new family of nonmobile colistin resistance (from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.