Evidence map›Paper›PMID 31179036›Full record

ArticleBMJ global health2019

Effect of an integrated neonatal care kit on neonatal health outcomes: a cluster randomised controlled trial in rural Pakistan.

Lisa G Pell, Ali Turab, Diego G Bassani, Joy Shi, Sajid Soofi, Masawar Hussain, Shabina Ariff, Zulfiqar A Bhutta, Shaun K Morris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Lisa G PellCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ali TurabDepartment of Paediatrics and Child Health, Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
Diego G BassaniCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Joy ShiDepartment of Epidemiology, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.
Sajid SoofiDepartment of Paediatrics and Child Health, Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
Masawar HussainDepartment of Paediatrics and Child Health, Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
Shabina AriffDepartment of Paediatrics and Child Health, Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
Zulfiqar A BhuttaCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Shaun K MorrisCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Aga Khan University · PKHospital for Sick Children · CAHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn 2016, 2.6 million children died during their first month of life. We assessed the effectiveness of an integrated neonatal care kit (iNCK) on neonatal survival and other health outcomes in rural Pakistan.

methodsWe conducted a community-based, cluster randomised, pragmatic, open-label, controlled intervention trial in Rahim Yar Khan, Punjab, Pakistan. Clusters, 150 villages and their lady health workers (LHWs), were randomly assigned to deliver the iNCK (intervention) or standard of care (control). In intervention clusters, LHWs delivered the iNCK and education on its use to pregnant women. The iNCK contained a clean birth kit, chlorhexidine, sunflower oil, a continuous temperature monitor (ThermoSpot), a heat reflective blanket and reusable heat pack. LHWs were also given a hand-held scale. The iNCK was implemented primarily by caregivers. The primary outcome was all-cause neonatal mortality. Outcomes are reported at the individual level, adjusted for cluster allocation. Enrolment took place between April 2014 and July 2015 and participant follow-up concluded in August 2015.

results5451 pregnant women (2663 and 2788 in intervention and control arms, respectively) and their 5286 liveborn newborns (2585 and 2701 in intervention and control arms, respectively) were enrolled. 147 newborn deaths were reported, 65 in the intervention arm (25.4 per 1000 live births) compared with 82 in the control arm (30.6 per 1000 live births). Neonatal mortality was not significantly different between treatment groups (risk ratio 0.83, 95% CI 0.58 - 1.18; p = 0.30).

conclusionProviding co-packaged interventions directly to women did not significantly reduce neonatal mortality. Further research is needed to improve compliance with intended iNCK use.

Indexed as

integrated interventionlady health workerneonatal mortalityPakistan

Identifiers

PMID31179036
PMCPMC6528753
OpenAlexW2945660004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.