ReviewCardiac failure review2019
Aortic Stenosis and Heart Failure: Disease Ascertainment and Statistical Considerations for Clinical Trials.
Review in Cardiac failure review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review, meta-analysis of cusp-overlap vs. three-cusp coplanar approaches in self-expandable transcatheter aortic valve replacement.Frontiers in cardiovascular medicine · 2026Pooled it
- Cusp-overlap view versus three cusp coplanar view during transcatheter aortic valve replacement using self-expandable valves: a systematic review, meta-analysis and meta-regression.BMC cardiovascular disorders · 2025Pooled it
- Detection of Biventricular Volume Increase in Overweight and Obese Individuals Using a Novel Index of the "Standard Human"-A Single-Center, Non-Contrast-Enhanced Cardiac CT Study.Journal of clinical medicine · 2026Article
- Longitudinal Outcomes of Left Ventricular Outflow Tract Obstruction in Aortic Stenosis Versus Hypertrophic Obstructive Cardiomyopathy.Medicina (Kaunas, Lithuania) · 2025Article
- Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ): Validation in Polish Patients with Aortic Stenosis.Journal of clinical medicine · 2025Article
- Computational study of transcatheter aortic valve replacement based on patient-specific models-rapid surgical planning for self-expanding valves.Frontiers in physiology · 2024Article
- Computational study of the balloon dilation steps on transcatheter aortic valve replacement.Frontiers in bioengineering and biotechnology · 2023Article
- Imaging Challenges in Patients with Severe Aortic Stenosis and Heart Failure: Did We Find a Way Out of the Labyrinth?Journal of clinical medicine · 2022Review
- Prognosis and outcome determinants after heart failure diagnosis in patients who underwent aortic valvular intervention.ESC heart failure · 2021Observational
- Cerebral microemboli in mini-sternotomy compared to mini- thoracotomy for aortic valve replacement: a cross sectional cohort study.Journal of cardiothoracic surgery · 2021Observational
- Decline in the Volume of Structural Heart Procedures in the United States Due to the COVID-19 Pandemic.Structural heart : the journal of the Heart TeamArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aortic stenosis is a progressive disease that develops over decades, and once symptomatic and untreated, is associated with poor survival. Transcatheter aortic valve replacement has evolved significantly in the past decade and has expanded its indication from surgically inoperable and high-risk patients to patients with intermediate risk. Assessment of heart failure-related outcomes include the use of functional assessments, disease-specific quality of life surveys and standardised ascertainment of events, such as hospitalisations. Multiple statistical approaches are currently being tested to account for recurrent events such as hospitalisations for heart failure or to combine binary and continuous outcomes, both intended to assess the holistic burden of the disease, as opposed to the traditional analysis of time to first event.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.