Evidence map›Paper›PMID 31178999›Full record

ArticleBMJ open respiratory research2019

Compliance after switching from CPAP to bilevel for patients with non-compliant OSA: big data analysis.

Adam V Benjafield, Jean-Louis Pépin, Kate Valentine, Peter A Cistulli, Holger Woehrle, Carlos M Nunez, Jeff Armitstead, Atul Malhotra

Abstract readComparative Study
In one paragraph

Article in BMJ open respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Walking the fine line between OSA and aging.Sleep & breathing = Schlaf & Atmung · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. CPAP setup by mail: we're not there yet.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  13. Article
  14. Treatment options in obstructive sleep apnea.Internal and emergency medicine · 2022
    Review
  15. Adherence Monitoring Using Telemonitoring Techniques.Advances in experimental medicine and biology · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam V BenjafieldResMed Science Center, San Diego, California, USA.ORCID 0000-0003-4716-2827
Jean-Louis PépinmedXcloud Group, San Diego, California, USA.
Kate ValentineResMed Science Center, San Diego, California, USA.
Peter A CistullimedXcloud Group, San Diego, California, USA.
Holger WoehrlemedXcloud Group, San Diego, California, USA.ORCID 0000-0001-6588-5039
Carlos M NunezResMed Science Center, San Diego, California, USA.
Jeff ArmitsteadmedXcloud Group, San Diego, California, USA.
Atul MalhotramedXcloud Group, San Diego, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: For patients with obstructive sleep apnoea (OSA) who are initially non-compliant with continuous (automatic) positive airway pressure (CPAP/APAP) therapy, a bilevel PAP (Spont/VAuto) therapy transition pathway is available to improve therapy adherence. The aim of this retrospective study was to compare PAP therapy usage data of patients with non-compliant OSA (ncOSA) on CPAP/APAP who were switched to bilevel PAP. Methods: A PAP telemonitoring database was queried between 1 January 2015 and 31 July 2016 for eligible patients started on CPAP/APAP and non-CMS (United States Center for Medicare and Medicaid Services) compliant and switched to bilevel PAP within 90 days of starting CPAP/APAP therapy. PAP therapy data on all patients were compared before switch (CPAP/APAP) and after switch (VAuto/Spont). Results: Of the 1496 patients with ncOSA identified, 30.3% used CPAP, 62.3% APAP, and 7.4% both APAP and CPAP before switching to a bilevel mode. 47.8% patients switched to Spont mode and 52.2% to VAuto mode. PAP usage significantly improved by 0.9 h/day (p<0.001) and all other device metrics (residual apnoea-hypopnoea index and unintentional mask leak) also improved after the switch. No patients had achieved US CMS criteria for compliance before the switch, and 56.8% did after. Conclusion: This shows for the first time that there may be potential benefit from switching from CPAP/APAP to bilevel PAP for patients struggling with PAP adherence.

Indexed as

Data AnalysisAdultAgedContinuous Positive Airway PressureHumansMiddle AgedPatient CompliancePolysomnographyRetrospective StudiesSleep Apnea, ObstructiveTelemetryUnited Statessleep apnoea

Identifiers

PMID31178999
PMCPMC6530496

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.