Evidence map›Paper›PMID 31178991›Full record

ArticleStat (International Statistical Institute)2019

Modelling and estimation for optimal treatment decision with interference.

Lin Su, Wenbin Lu, Rui Song

Abstract read
In one paragraph

Article in Stat (International Statistical Institute), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Dynamic Treatment Regimes on Dyadic Networks.Statistics in medicine · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lin SuDepartment of Statistics, North Carolina State University, Raleigh, North Carolina.
Wenbin LuDepartment of Statistics, North Carolina State University, Raleigh, North Carolina.ORCID 0000-0002-7320-4755
Rui SongDepartment of Statistics, North Carolina State University, Raleigh, North Carolina.

Funding

Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIDIAN, MARIE, KOSOROK, MICHAEL R · 2010 to 2019
$21.3M
NCI NIH HHS P01 CA142538
6 · The paper itself

Abstract

In many network-based intervention studies, treatment applied on an individual or his or her own characteristics may also affect the outcome of other connected people. We call this interference along network. Approaches for deriving the optimal individualized treatment regimen remain unknown after introducing the effect of interference. In this paper, we propose a novel network-based regression model that is able to account for interaction between outcomes and treatments in a network. Both Q-learning and A-learning methods are derived. We show that the optimal treatment regimen under our model is independent from interference, which makes its application in practice more feasible and appealing. The asymptotic properties of the proposed estimators are established. The performance of the proposed model and methods is illustrated by extensive simulation studies and an application to a mobile game network data.

Indexed as

A-learninginterferencenetworkoptimal treatment regimenQ-learning

Identifiers

PMID31178991
PMCPMC6551619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.