Evidence map›Paper›PMID 31178980›Full record

ArticleInternational IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering2019

A Novel Biomimetic Stimulator System for Neural Implant.

Po-Min Wang, Stanislav Culaclii, William Yang, Yan Long, Jonathan Massachi, Yi-Kai Lo, Wentai Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Po-Min WangDepartment of Bioengineering, University of California, Los Angeles, CA, 90095, USA.
Stanislav CulacliiDepartment of Bioengineering, University of California, Los Angeles, CA, 90095, USA.
William YangDepartment of Computer Science, University of California, Los Angeles, CA, 90095, USA.
Yan LongCollege of Electrical Engineering, Zhijiang University, Hangzhou, 310027, China.
Jonathan MassachiDepartment of Bioengineering, University of California, Los Angeles, CA, 90095, USA.
Yi-Kai LoNiche Biomedical Inc., Los Angeles, CA 90095, USA.
Wentai LiuDepartment of Bioengineering, University of California, Los Angeles, CA, 90095, USA.
University of California, Los Angeles · US

Funding

Spinal Epidural Electrode Array to Facilitate Standing and Stepping After SCIR01EB007615 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EDGERTON, REGGIE · 2008 to 2013
$4.9M
Spinal Epidural Electrode Array To Facilitate Standing and Stepping After SCIU01EB007615 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EDGERTON, REGGIE, GAD, PARAG · 2014 to 2018
$4.8M
NIBIB NIH HHS R01 EB007615NIBIB NIH HHS U01 EB007615
6 · The paper itself

Abstract

Electrical stimulation using non-periodic biomimetic stimulation pattern has been shown to be effective in various critical biomedical applications. However, the existing programmable stimulators that support this protocol are non-portable and have architectures that are not translatable to wearable or implantable applications. In this work, we present a 32-channel neural stimulator system based on an implantable System-On-Chip (SoC) that addresses these technological challenges. The system is designed to be portable, powered by a single battery, wirelessly controlled, and versatile to perform concurrent multi-channel stimulation with independent arbitrary waveforms. The experimental results demonstrate multi-channel stimulation mimicking electromyography (EMG) waveforms and randomly-spaced stimulation pulses mimicking neuronal firing patterns. This compact and highly flexible prototype can support various neuromodulation researches and animal studies and serves as a precursor for the development of the next generation implantable biomimetic stimulator.

Identifiers

PMID31178980
PMCPMC6553867
OpenAlexW2946275551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.