ArticleBehavioural neurology2019
Medication Belief and Adherence among Patients with Epilepsy.
Article in Behavioural neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors Associated With Antiseizure Medication Adherence in Patients With Epilepsy: A Systematic Review.Brain and behavior · 2026Pooled it
- Health-related quality of life and associated factors among patients living with epilepsy of Mekelle City Hospitals, Northern Ethiopia: a multicenter observational study.Health and quality of life outcomes · 2026Observational
- Etiology, Symptoms, and Treatment of Epilepsy: Advances and Perspectives.Brain sciences · 2026Article
- Medication adherence in epilepsy: the role of adverse drug reactions and patient knowledge-attitude-behavior.Acta epileptologica · 2026Article
- Bayesian-Based Pharmacokinetic Framework Integrated with Therapeutic Drug Monitoring for Assessing Adherence to Antiseizure Medications: A Clinical Trial Simulation Study.Journal of medical Internet research · 2026Article
- Barriers and facilitators of antiseizure medication adherence: a qualitative study among persons with epilepsy in Pakistan.BMC neurology · 2025Article
- Prevalence and determinants of uncontrolled seizures in adult people with epilepsy attending comprehensive specialized hospitals in Northwest Amhara, Ethiopia: a multicenter study.BMC public health · 2025Article
- Observational
- Barriers to Medication Adherence in People Living With Epilepsy.Neurology. Clinical practice · 2025Article
- Multicentric study of adherence to antiseizure medications among adults with epilepsy attended in neurology departments in Burkina Faso.Epilepsia open · 2025Article
- Development and Validation of a New Adherence Scale for Antiseizure Medications [ASASM].Journal of clinical medicine · 2024Article
- Non-Adherence to Antiseizure Medications: Rate and Predictors in Saudi Arabia.Medicina (Kaunas, Lithuania) · 2024Article
- A study to assess medication adherence and quality of life among epilepsy patients seeking treatment at AIIMS Bhopal.Journal of family medicine and primary care · 2024Article
- Article
- Adherence with oral nutritional supplements and influencing factors in postoperative patients with digestive tract tumors: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Pharmacist's Impact on Medication Adherence and Drug-Related Problems in Patients with Epilepsy.Turkish journal of pharmaceutical sciences · 2024Article
- Observational
- Quality of life among caregivers of epileptic children with degree of controlling seizures in Aseer region.Journal of family medicine and primary care · 2022Article
- Antiepileptic Drug Adherence and Its Associated Factors among Epilepsy Patients on Follow-ups at Amanuel Mental Specialized Hospital, Ethiopia.Ethiopian journal of health sciences · 2022Article
- Detecting Reasons for Nonadherence to Medication in Adults with Epilepsy: A Review of Self-Report Measures and Key Predictors.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMedication adherence and belief are crucial to achieving the desired goal of therapy in epileptic patients. However, there is a lack of study regarding medication adherence and belief in our setting. Therefore, the purpose of this study was to investigate medication adherence and belief and associated factors among ambulatory patients with epilepsy.
methodA cross-sectional study was conducted on randomly selected epileptic patients at the neurologic clinic of Ayder Comprehensive Specialized Hospital, Ethiopia. Medication adherence and belief were assessed using self-reported questionnaires which were developed based on the review of different literatures. Data were analyzed using binary logistic regression analysis.
resultWe included a total of 292 patients. Almost two-thirds (65.4%) of the patients were nonadherent to their medications. The most common cause of nonadherence was forgetfulness (48.7%) followed by inability to get medicine (28.8) and safety concern (23.5%). The majority (78.4%) of the patients had high medication necessity belief while 44.1% had high concern belief about the potential adverse effect of their medications. Overall, 39.4% of the patients had a negative belief toward their medications. Comorbidity (AOR: 3.51, 95% CI: 1.20-10.31), seizure encounter within the last 3 months (AOR: 5.45, 95% CI: 2.48-12.00), low medication necessity belief (AOR: 3.38, 95% CI: 1.14-10.00), high medication concern belief (AOR: 4.23, 95% CI: 2.07-8.63), and negative medication belief (AOR: 4.17, 95% CI: 1.74-10.02) were predictors of medication nonadherence.
conclusionMajority of the epileptic patients were nonadherent to their medications, and more than one-third of the patients had a negative medication belief. Low medication necessity belief, high medication concern belief, negative medication belief, comorbidity, and seizure encounter were predictors of medication nonadherence. Therefore, healthcare providers should design educational programs to enhance the patients' believe about their medication in order to improve medication adherence and overall treatment outcome.
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