Evidence map›Paper›PMID 31178933›Full record

ReviewInterventional cardiology (London, England)2019

How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial.

Thomas J Ford, Colin Berry

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Interventional cardiology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03193294 nacompletednot on this map

CORonary MICrovascular Angina (CorMicA): a Randomised, Controlled, Pilot Trial

TypeinterventionalSponsorNHS National Waiting Times Centre BoardRan2016 to 2019Enrolled151ConditionsAngina, Stable, Coronary Vasospasm, Coronary Circulation, Coronary SyndromeArmsStratified medicine involving a diagnostic intervention
NCT05009667 completednot on this mapstarted 2021, after this paper: background citation

A Prospective, Multi-center Clinical Trial for Evaluating the Effectiveness and Safety of Coronary Angiography-Derived Index of Microcirculatory Resistance Measured Online by a Coronary Functional Measurement System

TypeobservationalSponsorGe JunboRan2021 to 2021Enrolled116ConditionsCoronary Microvascular DysfunctionArmsAngiography-derived Index of Microcirculatory Resistance, Pressure wire-based Index of Microcirculatory Resistance
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
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  6. Article
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  8. Review
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  11. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA).Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Comparison of 2D-QCA, 3D-QCA and coronary angiography derived FFR in predicting myocardial ischemia assessed by CZT-SPECT MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas J FordWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital UK.
Colin BerryWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital UK.
University of Glasgow · GB

Funding

British Heart Foundation PG/17/25/32884
6 · The paper itself

Abstract

Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge. Microvascular and/or vasospastic angina are the two most common causes of INOCA; however, invasive coronary angiography lacks the sensitivity to diagnose these functional coronary disorders. In this article, the authors summarise the rationale for invasive testing in the absence of obstructive coronary disease, namely that correct treatment for angina patients starts with the correct diagnosis. They provide insights from the CORonary MICrovascular Angina (CorMicA) study, where an interventional diagnostic procedure was performed with linked medical therapy to improve patient health. Identification of these distinct disorders (microvascular angina, vasospastic angina or non-cardiac chest pain) is key for stratifying INOCA patients, allowing prognostic insights and better patient care with linked therapy based on contemporary guidelines. Finally, they propose a framework to diagnose and manage patients in this common clinical scenario.

Indexed as

coronary physiologycoronary vasoreactivity testingelective coronary angiographyischaemiamicrovascular anginaStable angina pectorisvasospastic angina

Identifiers

PMID31178933
PMCPMC6545998
OpenAlexW2944833754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.