Evidence map›Paper›PMID 31178904›Full record

ArticleNeural plasticity2019

Fast Recovery of the Amblyopic Eye Acuity of Kittens following Brief Exposure to Total Darkness Depends on the Fellow Eye.

Donald E Mitchell, Elise Aronitz, Philip Bobbie-Ansah, Nathan Crowder, Kevin R Duffy

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. A randomized clinical trial of contrast increment protocols for binocular amblyopia treatment.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2020
    Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donald E MitchellDepartment of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada B3H 4R2.ORCID 0000-0002-3441-6333
Elise AronitzDepartment of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada B3H 4R2.
Philip Bobbie-AnsahDepartment of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada B3H 4R2.
Nathan CrowderDepartment of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada B3H 4R2.ORCID 0000-0002-3168-1692
Kevin R DuffyDepartment of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada B3H 4R2.ORCID 0000-0003-3871-3287
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies conducted on kittens have revealed that the reduced visual acuity of the deprived eye following a short period of monocular deprivation imposed in early life is reversed quickly following a 10-day period spent in total darkness. This study explored the contribution of the fellow eye to the darkness-induced recovery of the acuity of the deprived eye. Upon emergence of kittens from darkness, the fellow eye was occluded for different lengths of time in order to investigate its effects on either the speed or the extent of the recovery of acuity of the deprived eye. Occlusion of the fellow eye for even a day immediately following the period spent in darkness blocked any recovery of the acuity of the deprived eye. Moreover, occlusion of the fellow eye two days after the period of darkness blocked any further visual recovery beyond that achieved in the short period when both eyes were open. The results imply that the darkness-induced recovery of the acuity of the deprived eye depends upon, and is guided by, neural activity in the mature neural connections previously established by the fellow eye.

Indexed as

Ocular Physiological PhenomenaAmblyopiaAnimalsCatsDarknessEyeSensory DeprivationVision, Ocular

Identifiers

PMID31178904
PMCPMC6507257
OpenAlexW2940782914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.