Evidence map›Paper›PMID 31178732›Full record

ArticleFrontiers in pharmacology2019

Enaminone Modulators of Extrasynaptic α

Timothy B C Johnstone, Hilary S McCarren, Jay Spampanato, F Edward Dudek, John H McDonough, Derk Hogenkamp, Kelvin W Gee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Allosteric modulators of the δ GABANeuropharmacology · 2022
    Article
  3. The KNeuroscience · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Timothy B C JohnstoneDepartment of Pharmacology, School of Medicine, University of California, Irvine, Irvine, CA, United States.
Hilary S McCarrenNeuroscience Department, Medical Toxicology Research Division, United States Army Research Institute of Chemical Defense, Aberdeen, MD, United States.
Jay SpampanatoDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, United States.
F Edward DudekDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, United States.
John H McDonoughNeuroscience Department, Medical Toxicology Research Division, United States Army Research Institute of Chemical Defense, Aberdeen, MD, United States.
Derk HogenkampDepartment of Pharmacology, School of Medicine, University of California, Irvine, Irvine, CA, United States.
Kelvin W GeeDepartment of Pharmacology, School of Medicine, University of California, Irvine, Irvine, CA, United States.
University of California, Irvine · USUnited States Army · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABA

Indexed as

diisopropyl fluorophosphateextrasynapticmidazolamnerve agentsomanγ-aminobutyric acid-A receptors

Identifiers

PMID31178732
PMCPMC6543275
OpenAlexW2945261311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.