Evidence map›Paper›PMID 31178655›Full record

ArticleSarcoma2019

Role of Radiation Therapy in Adult Extraskeletal Ewing's Sarcoma Patients Treated with Chemotherapy and Surgery.

Augustine M Saiz, Alicia A Gingrich, Robert J Canter, Amanda R Kirane, Arta M Monjazeb, R Lor Randall, Steven W Thorpe

Open access · hybridAbstract read
In one paragraph

Article in Sarcoma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Augustine M SaizSarcoma Services, MSK Section, Department of Orthopaedic Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0002-1955-8667
Alicia A GingrichDivision of Surgical Oncology, Department of Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.
Robert J CanterDivision of Surgical Oncology, Department of Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.
Amanda R KiraneDivision of Surgical Oncology, Department of Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.
Arta M MonjazebDepartment of Radiation Oncology, UC Davis Medical Center, Sacramento, CA 95817, USA.
R Lor RandallSarcoma Services, MSK Section, Department of Orthopaedic Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.
Steven W ThorpeSarcoma Services, MSK Section, Department of Orthopaedic Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0003-3127-4912
University of California Davis Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation therapy (RT) is advocated in the multimodal treatment of high-grade soft tissue sarcoma (STS), but its role may be less clear in chemotherapy-sensitive STS such as extraskeletal Ewing sarcoma (EES). The purpose of this study was to determine the role of RT on overall survival (OS) in localized EES adult patients treated with chemotherapy and surgery. Adult patients diagnosed with EES and reported to the National Cancer Database from 2004 to 2014 were evaluated. All patients were treated with surgical resection. Patient demographics, tumor characteristics, treatments received, resection margins, and survival were examined for the 232 patients identified. Using multivariate analysis and Cox proportional hazard analysis, predictors of OS were determined. In the overall cohort, 40 percent of patients received RT and 78 percent received chemotherapy, with 31 percent receiving both. The addition of RT to the patients receiving surgery + chemotherapy did not improve OS (

Identifiers

PMID31178655
PMCPMC6507246
OpenAlexW2940544327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.