Evidence map›Paper›PMID 31178620›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2017

Cranial thickness changes in early childhood.

Niharika Gajawelli, Sean Deoni, Jie Shi, Holly Dirks, Marius George Linguraru, Marvin D Nelson, Yalin Wang, Natasha Lepore

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Niharika GajawelliCIBORG Lab, Department of Radiology, Children's Hospital Los Angeles, CA, USA.
Sean DeoniDepartment of Pediatric Radiology Research, Children's Hospital Colorado, CO, USA.
Jie ShiDepartment of Computer Science, Arizona State University, AZ, USA.
Holly DirksDepartment of Biomedical Engineering, Brown University, RI, USA.
Marius George LinguraruSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, Washington DC.
Marvin D NelsonDepartment of Radiology, University of Southern California, CA, USA.
Yalin WangDepartment of Computer Science, Arizona State University, AZ, USA.
Natasha LeporeCIBORG Lab, Department of Radiology, Children's Hospital Los Angeles, CA, USA.
University of Southern California · USArizona State University · USBrown University · USGeorge Washington University · US

Funding

Statistical Methods for Brain Image Registration and Tensor-Based MorphometryR21EB012177 · NIBIB · CHILDREN'S HOSPITAL OF LOS ANGELES · PI LEPORE, NATASHA · 2011 to 2012
$478k
NIBIB NIH HHS R21 EB012177
6 · The paper itself

Abstract

The neurocranium changes rapidly in early childhood to accommodate the developing brain. However, developmental disorders may cause abnormal growth of the neurocranium, the most common one being craniosynostosis, affecting about 1 in 2000 children. It is important to understand how the brain and neurocranium develop together to understand the role of the neurocranium in neurodevelopmental outcomes. However, the neurocranium is not as well studied as the human brain in early childhood, due to a lack of imaging data. CT is typically employed to investigate the cranium, but, due to ionizing radiation, may only be used for clinical cases. However, the neurocranium is also visible on magnetic resonance imaging (MRI). Here, we used a large dataset of MRI images from healthy children in the age range of 1 to 2 years old and extracted the neurocranium. A conformal geometry based analysis pipeline is implemented to determine a set of statistical atlases of the neurocranium. A growth model of the neurocranium will help us understand cranial bone and suture development with respect to the brain, which will in turn inform better treatment strategies for neurocranial disorders.

Indexed as

brainneonatal/pediatric imagingNeurocranium

Identifiers

PMID31178620
PMCPMC6554209
OpenAlexW2770204149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.