Evidence map›Paper›PMID 31178604›Full record

ArticleMonatshefte fur chemie2019

Synthesis of modified 1,5-imino-d-xylitols as ligands for lysosomal

Manuel Zoidl, Andreas Wolfsgruber, Michael Schalli, Seyed A Nasseri, Patrick Weber, Arnold E Stütz, Stephen G Withers, Tanja M Wrodnigg

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Monatshefte fur chemie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Manuel Zoidl1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.
Andreas Wolfsgruber1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.
Michael Schalli1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.
Seyed A Nasseri2Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1 Canada.
Patrick Weber1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.
Arnold E Stütz1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.
Stephen G Withers2Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1 Canada.
Tanja M Wrodnigg1Institute of Organic Chemistry, Graz University of Technology, Graz, Austria.ORCID 0000-0002-7644-5431
Graz University of Technology · ATUniversity of British Columbia · CA

Funding

Austrian Science Fund FWF P 30372
6 · The paper itself

Abstract

abstractModified 1,5-dideoxy-1,5-imino-d-xylitol analogues with different substitution patterns involving position C-1 and/or the ring nitrogen were prepared, which were designed to serve as precursors for the preparation of iminoxylitol-based ligands and tools for the elucidation and modulation of human lysosomal GRAPHICAL ABSTRACT:

Indexed as

CarbohydratesConformationEnzymesIminoxylitolβ-Glucocerebrosidaseβ-Glucosidase ligands

Identifiers

PMID31178604
PMCPMC6534063
OpenAlexW2944691708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.