Evidence map›Paper›PMID 31178507›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Osteosarcoma Manifesting Systemic Inflammation and Histological Features Mimicking Plasma Cell-type Castleman Disease.

Shino Fujimoto, Tomoyuki Sakai, Hiroshi Kawabata, Nozomu Kurose, Sohsuke Yamada, Mariko Doai, Munetaka Matoba, Haruka Iwao-Kawanami, Takafumi Kawanami, Shuichi Mizuta and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Castleman disease and TAFRO syndrome.Annals of hematology · 2022
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Shino FujimotoDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Tomoyuki SakaiDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Hiroshi KawabataDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Nozomu KuroseDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Japan.
Sohsuke YamadaDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Japan.
Mariko DoaiDepartment of Radiology, Kanazawa Medical University, Japan.
Munetaka MatobaDepartment of Radiology, Kanazawa Medical University, Japan.
Haruka Iwao-KawanamiDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Takafumi KawanamiDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Shuichi MizutaDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Toshihiro FukushimaDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Hiroki MizumakiDepartment of Hematology, Ishikawa Prefectural Central Hospital, Japan.
Masaki YamaguchiDepartment of Hematology, Ishikawa Prefectural Central Hospital, Japan.
Yasufumi MasakiDepartment of Hematology and Immunology, Kanazawa Medical University, Japan.
Kanazawa Medical University · JPIshikawa Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old man was referred to our hospital with a persistent fever, anemia, and a mass in the left pubic region. The findings of biopsy evaluations of the mass and a left inguinal lymph node were consistent with Castleman disease (CD) of plasma cell type. His serum interleukin 6 (IL-6) level was remarkably elevated, supporting the diagnosis of CD. However, imaging analyses revealed destruction of the pubic bone by the mass, which was atypical for CD. Therefore, another deeper biopsy was performed, which finally led to the diagnosis of IL-6-producing osteosarcoma. We conclude that clinicians should carefully exclude malignancies prior to making a CD diagnosis.

Indexed as

AgedAnemiaBiopsyBone NeoplasmsCastleman DiseaseDiagnosis, DifferentialFeverHumansInflammationInterleukin-6Lymph NodesMaleOsteosarcomaPlasma CellsPubic BoneInterleukin-6Castleman diseasediagnosisinterleukin 6osteosarcoma

Identifiers

PMID31178507
PMCPMC6761330
OpenAlexW2950315464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.