Evidence map›Paper›PMID 31178483›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Pulmonary Mycobacterium abscessus Subspecies abscessus Disease That Showed a Discrepancy Between the Genotype and Phenotype of Clarithromycin Resistance.

Yusuke Yamaba, Osamu Takakuwa, Manami Saito, Daisuke Kawae, Misuzu Yoshihara, Yuta Mori, Eiji Kunii, Yutaka Ito, Shiomi Yoshida, Kenji Akita

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Antibiotic Resistance Genes and Associated Phenotypes inAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yusuke YamabaDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Osamu TakakuwaDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Manami SaitoDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Daisuke KawaeDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Misuzu YoshiharaDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Yuta MoriDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Eiji KuniiDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Yutaka ItoDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Japan.
Shiomi YoshidaDepartment of Clinical Research Center, National Hospital Organization Kinki-chuo Chest Medical Center, Japan.
Kenji AkitaDepartment of Respiratory Medicine, Nagoya City West Medical Center, Japan.
Nagoya Medical Center · JPNagoya City University · JPNational Kinki Chuo Hospital for Chest Disease · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium abscessus subspecies abscessus is major subspecies in the M. abscessus complex and is usually refractory to standard antibiotherapy. Genetic tracing of erm (41) T28 is a mechanism for monitoring macrolide resistance. We treated a patient with a pulmonary infection caused by M. abscessus subsp. abscessus with the erm (41) T28 polymorphism, which was susceptible to clarithromycin, and his clinical treatment course was good. The identification of the M. abscessus complex genotype is important, but clinical confirmation of clarithromycin susceptibility is also needed to plan individual treatment strategies.

Indexed as

Anti-Bacterial AgentsClarithromycinDrug Resistance, BacterialGenotypeHumansMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium abscessusMycobacterium Infections, NontuberculousPhenotypeTuberculosis, PulmonaryAnti-Bacterial AgentsClarithromycinerm (41)inducible resistanceMycobacterium abscessus

Identifiers

PMID31178483
PMCPMC6794162
OpenAlexW2972645546

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.