Evidence map›Paper›PMID 31178154›Full record

ReviewLancet (London, England)2019

The public health control of scabies: priorities for research and action.

Daniel Engelman, Paul T Cantey, Michael Marks, Anthony W Solomon, Aileen Y Chang, Olivier Chosidow, Wendemagegn Enbiale, Dirk Engels, Roderick J Hay, David Hendrickx and 14 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Lancet (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04931680 (Risk Factors for Treatment Failure of Scabies in Autochthonous Populations of French Guiana), which is not on this map. Cited by 102 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 5 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04931680 unknown statusnot on this mapstarted 2021, after this paper: background citation

Risk Factors for Treatment Failure of Scabies in Autochthonous Populations of French Guiana (GUYAGALE)

TypeobservationalSponsorCentre Hospitalier de CayenneRan2021 to 2021Enrolled276ConditionsScabiesArmsData collection
3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 5 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Prevalence and determinants of scabies: A global systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2024
    Pooled it
  3. Pooled it
  4. Mass Drug Administration for the Control of Scabies: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Pooled it
  5. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 7 countries.

Daniel EngelmanTropical Diseases Group, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of General Medicine, Royal Children's Hospital, Melbourne, VIC, Australia. Electronic address: daniel.engelman@rch.org.au.
Paul T CanteyDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Michael MarksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Anthony W SolomonDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Aileen Y ChangDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Olivier ChosidowDepartment of Dermatology, Hôpital Henri-Mondor, Assistance Publique Hôpitaux de Paris, Créteil, France; Université Paris-Est Créteil Val-de-Marne, Créteil, France.
Wendemagegn EnbialeDepartment of Dermatovenerology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Dirk EngelsUniting to Combat Neglected Tropical Diseases, Switzerland.
Roderick J HayDepartment of Dermatology, King's College London, London, UK.
David HendrickxTelethon Kids Institute, University of Western Australia, Perth, WA, Australia.
Peter J HotezNational School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.
John M KaldorThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Mike KamaMinistry of Health and Medical Services, Suva, Fiji.
Charles D MackenzieThe Taskforce for Global Health, Decatur, GA, USA.
James S McCarthyQIMR Berghoefer Medical Research Institute, Brisbane, QLD, Australia.
Diana L MartinDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Birhan MengistuFederal Ministry of Health, Addis Ababa, Ethiopia.
Toby MaurerDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Nebiyu NegussuFederal Ministry of Health, Addis Ababa, Ethiopia.
Lucia RomaniThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Oliver SokanaMinistry of Health and Medical Services, Honiara, Solomon Islands.
Margot J WhitfeldDepartment of Dermatology, St Vincent's Hospital, University of New South Wales, Sydney, NSW, Australia.
L Claire FullerChelsea and Westminster Healthcare National Health Service Foundation Trust, London, UK; International Foundation for Dermatology, London, UK.
Andrew C SteerTropical Diseases Group, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of General Medicine, Royal Children's Hospital, Melbourne, VIC, Australia.
Federal Ministry of Health · ETMurdoch Children's Research Institute · AUUniversity of California, San Francisco · USUNSW Sydney · AUWorld Health Organization · CHBahir Dar University · ETBaylor College of Medicine · USCenters for Disease Control and Prevention · USChelsea and Westminster Hospital NHS Foundation Trust · GBDrugs for Neglected Diseases Initiative · CHKing's College London · GBLondon School of Hygiene & Tropical Medicine · GBMinistry Of Health · FJQIMR Berghofer Medical Research Institute · AUSt Vincent's Hospital · AUThe Task Force for Global Health · USUniversité Paris-Est Créteil · FRUniversity of Western Australia · AU

Funding

Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

Scabies is a parasitic disease of the skin that disproportionately affects disadvantaged populations. The disease causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease. Scientific advances from the past 5 years suggest that scabies is amenable to population-level control, particularly through mass drug administration. In recognition of these issues, WHO added scabies to the list of neglected tropical diseases in 2017. To develop a global control programme, key operational research questions must now be addressed. Standardised approaches to diagnosis and methods for mapping are required to further understand the burden of disease. The safety of treatments for young children, including with ivermectin and moxidectin, should be investigated. Studies are needed to inform optimum implementation of mass treatment, including the threshold for intervention, target, dosing, and frequency. Frameworks for surveillance, monitoring, and evaluation of control strategies are also necessary.

Indexed as

Global HealthHumansMass Drug AdministrationNeglected DiseasesPopulation SurveillancePublic HealthScabiesWorld Health Organization

Identifiers

PMID31178154
PMCPMC11257500
OpenAlexW2948825612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.