Evidence map›Paper›PMID 31178123›Full record

ReviewTrends in microbiology2019

Surveying Gut Microbiome Research in Africans: Toward Improved Diversity and Representation.

Ryan Brewster, Fiona B Tamburini, Edgar Asiimwe, Ovokeraye Oduaran, Scott Hazelhurst, Ami S Bhatt

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Examining the healthy human microbiome concept.Nature reviews. Microbiology · 2025
    Review
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  20. The African Human Microbiome Portal: a public web portal of curated metagenomic metadata.Database : the journal of biological databases and curation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan BrewsterSchool of Medicine, Stanford University, Stanford, CA, USA.
Fiona B TamburiniDepartment of Genetics, Stanford University, Stanford, CA, USA.
Edgar AsiimweSchool of Medicine, Stanford University, Stanford, CA, USA.
Ovokeraye OduaranSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Scott HazelhurstSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa; School of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: Scott.Hazelhurst@wits.ac.za.
Ami S BhattSchool of Medicine, Stanford University, Stanford, CA, USA; Department of Genetics, Stanford University, Stanford, CA, USA; Department of Medicine (Hematology), Stanford University, Stanford, CA, USA. Electronic address: asbhatt@stanford.edu.

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
Sequence-based pathogen discovery in post-stem cell transplantation syndromesK08CA184420 · NCI · STANFORD UNIVERSITY · PI BHATT, AMI SIDDHARTH · 2014 to 2017
$524k
FIC NIH HHS R25 TW009338NCI NIH HHS K08 CA184420NHGRI NIH HHS T32 HG000044
6 · The paper itself

Abstract

Descriptive and translational investigations into the human gut microbiome (GM) are rapidly expanding; however, studies are largely restricted to industrialized populations in the USA and Europe. Little is known about microbial variability and its implications for health and disease in other parts of the world. Populations in Africa are particularly underrepresented. What limited research has been performed has focused on a few subject domains, including the impact of long-term lifestyle and dietary factors on GM ecology, its maturation during infancy, and the interrelationships between the microbiome, infectious disease, and undernutrition. Recently, international consortia have laid the groundwork for large-scale genomics and microbiome studies on the continent, with a particular interest in the epidemiologic transition to noncommunicable disease. Here, we survey the current landscape of GM scholarship in Africa and propose actionable recommendations to improve research capacity and output.

Indexed as

BiodiversityGastrointestinal MicrobiomeAfricaBiotechnologyCommunicable DiseasesComputational BiologyDietEcologyGenomicsGlobal HealthHumansLife StyleNutritional StatusAfricaglobal healthmicrobiome

Identifiers

PMID31178123
PMCPMC6764420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.