Evidence map›Paper›PMID 31177540›Full record

ArticleThe Journal of physiology2020

Diurnal properties of voltage-gated Ca

Beth A McNally, Amber E Plante, Andrea L Meredith

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Comparative CaBiophysical reports · 2021
    Article
  8. BK channel activation by L-type CaJournal of neurophysiology · 2021
    Article
  9. Contributions of CaFrontiers in physiology · 2021
    Article
  10. Review
  11. Calcium and cell function.The Journal of physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Beth A McNallyDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Amber E PlanteDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Andrea L MeredithDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.ORCID 0000-0003-1061-2302
University of Maryland, Baltimore · US

Funding

Daily Regulation of Ionic CurrentsR01HL102758 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2010 to 2024
$6.3M
TRAINING PROGRAM IN INTEGRATIVE MEMBRANE BIOLOGYT32GM008181 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI RIZZO, MEGAN A, TRUDEAU, MATTHEW C · 1987 to 2022
$4.9M
Multiparametric Biosensor Imaging in Brain SlicesR01MH111527 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANPIED, THOMAS A, MEREDITH, ANDREA L · 2016 to 2018
$1.6M
NHLBI NIH HHS R01 HL102758NIGMS NIH HHS T32 GM008181NIMH NIH HHS R01 MH111527
6 · The paper itself

Abstract

key pointsCircadian oscillations in spontaneous action potential firing in the suprachiasmatic nucleus (SCN) translate time-of-day throughout the mammalian brain. The ion channels that regulate the circadian pattern of SCN firing have not been comprehensively identified. Ca ABSTRACT: The mammalian circadian clock encodes time via rhythmic action potential activity in the suprachiasmatic nucleus (SCN) of the hypothalamus, which governs daily rhythms in physiology and behaviour. SCN neurons exhibit 24 h oscillations in spontaneous firing, with higher firing during day compared to night. Several ionic currents have been identified that regulate SCN firing, including voltage-gated Ca

Indexed as

Circadian ClocksNeuronsAction PotentialsAnimalsCalcium Channel BlockersCircadian RhythmSuprachiasmatic NucleusCalcium Channel Blockersaction potentialCa2+ currentscircadian rhythmintrinsic excitabilitysuprachiasmatic nucleusvoltage-gated Ca2+ channel

Identifiers

PMID31177540
PMCPMC6899208
OpenAlexW2948447288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.