Evidence map›Paper›PMID 31177288›Full record

ArticleArchivum immunologiae et therapiae experimentalis2019

Diverse Activity of IL-17

Aleksandra Klimczak, Krzysztof Suchnicki, Mariola Sedzimirska, Andrzej Lange

Open access · hybridAbstract read
In one paragraph

Article in Archivum immunologiae et therapiae experimentalis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aleksandra KlimczakHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114, Wroclaw, Poland. aleksandra.klimczak@hirszfeld.pl.ORCID http://orcid.org/0000-0001-6590-4420
Krzysztof SuchnickiLower Silesian Center for Cellular Transplantation and National Bone Marrow Donor Registry, Wroclaw, Poland.
Mariola SedzimirskaLower Silesian Center for Cellular Transplantation and National Bone Marrow Donor Registry, Wroclaw, Poland.
Andrzej LangeHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114, Wroclaw, Poland.
Ludwik Hirszfeld Institute of Immunology and Experimental Therapy · PL

Funding

Polish Ministry of Science & Higher Education N N402 430039
6 · The paper itself

Abstract

Excessive inflammatory environment in a course of chronic graft-versus-host disease (cGvHD) is associated with T-cell trafficking into inflamed tissues. This study focused on the identification of IL-17-producing cells in the tissue biopsies of cGvHD patients. Forty-one biopsy specimens of cGvHD lesions of the skin (n = 27), gastrointestinal tract (n = 9) and oral mucosa (n = 5), examined in 24 patients, were morphologically defined according to the NIH criteria and analyzed for the presence of cellular infiltrations including: IL-17

Indexed as

AdultChronic DiseaseFemaleForkhead Transcription FactorsGastrointestinal TractGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansInterleukin-17LymphocytesMaleMiddle AgedMouth MucosaOrgan SpecificityReceptors, CCR6Retrospective StudiesCCR6 protein, humanForkhead Transcription FactorsFOXP3 protein, humanIL17A protein, humanInterleukin-17Receptors, CCR6Chronic GvHDGraft-versus-host diseaseIL-17-producing cellsSkin and mucosa

Identifiers

PMID31177288
PMCPMC6732123
OpenAlexW2948327046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.