Evidence map›Paper›PMID 31176755›Full record

ReviewAdvanced drug delivery reviews2019

Electrically conductive nanomaterials for cardiac tissue engineering.

Khadijeh Ashtari, Hojjatollah Nazari, Hyojin Ko, Peyton Tebon, Masoud Akhshik, Mohsen Akbari, Sanaz Naghavi Alhosseini, Masoud Mozafari, Bita Mehravi, Masoud Soleimani and 4 more

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced drug delivery reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 1 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 1 synthesis or guideline pooled it, 228 citations in OpenAlex.

  1. Pooled it
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  14. Advances in nanostructured drug delivery systems for cardiovascular therapeutics.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
    Review
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  16. Article
  17. Review
  18. Stimuli-responsive hybrid materials for 4DMaterials today. Bio · 2025
    Review
  19. Review
  20. [Advances in hydrogel drug delivery systems for myocardial infarction treatment].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 5 countries.

Khadijeh AshtariRadiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran; Faculty of Advanced Technologies in Medicine, Department of Medical Nanotechnology, Iran University of Medical Sciences, Tehran, Iran; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Hojjatollah NazariFaculty of Advanced Technologies in Medicine, Department of Medical Nanotechnology, Iran University of Medical Sciences, Tehran, Iran; Stem Cell Technology Research Center, Tehran, Iran.
Hyojin KoCenter for Minimally Invasive Therapeutics (C-MIT), University of California - Los Angeles, Los Angeles, USA; Department of Bioengineering, University of California - Los Angeles, Los Angeles, USA.
Peyton TebonCenter for Minimally Invasive Therapeutics (C-MIT), University of California - Los Angeles, Los Angeles, USA; Department of Bioengineering, University of California - Los Angeles, Los Angeles, USA.
Masoud AkhshikFaculty of Forestry, University of Toronto, Toronto, Canada; Center for Biocomposites and Biomaterials Processing (CBBP), University of Toronto, Toronto, Canada; Shahdad Ronak Commercialization Company, Tehran, Iran.
Mohsen AkbariLaboratory for Innovations in MicroEngineering (LiME), Department of Mechanical Engineering, University of Victoria, Victoria, Canada; Center for Biomedical Research, University of Victoria, Victoria, Canada; Center for Advanced Materials and Related Technologies, University of Victoria, Victoria, Canada.
Sanaz Naghavi AlhosseiniBiomaterials Group, Department of Biomaterial Engineering, Amirkabir University of Technology, Tehran, Iran; Stem Cell Technology Research Center, Tehran, Iran.
Masoud MozafariLunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada.
Bita MehraviRadiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran; Faculty of Advanced Technologies in Medicine, Department of Medical Nanotechnology, Iran University of Medical Sciences, Tehran, Iran; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Masoud SoleimaniFaculty of Medical Sciences, Department of Hematology and Cell Therapy, Tarbiat Modares University, Tehran, Iran.
Reza ArdehaliDivision of Cardiology, Department of Internal Medicine, David Geffen School of Medicine, University of California - Los Angeles, USA.
Majid Ebrahimi WarkianiSchool of Biomedical Engineering, University of Technology Sydney, Sydney, Australia; Institute of Molecular Medicine, Sechenov University, Moscow, Russia.
Samad AhadianCenter for Minimally Invasive Therapeutics (C-MIT), University of California - Los Angeles, Los Angeles, USA; Department of Bioengineering, University of California - Los Angeles, Los Angeles, USA.
Ali KhademhosseiniCenter for Minimally Invasive Therapeutics (C-MIT), University of California - Los Angeles, Los Angeles, USA; Department of Bioengineering, University of California - Los Angeles, Los Angeles, USA; Department of Chemical and Biomolecular Engineering, University of California - Los Angeles, Los Angeles, USA; Department of Radiology, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, USA. Electronic address: khademh@ucla.edu.
University of California, Los Angeles · USIran University of Medical Sciences · IRStem Cell Technology Research Center · IRLunenfeld-Tanenbaum Research Institute · CATarbiat Modares University · IRUniversity of Technology Sydney · AUUniversity of Toronto · CAUniversity of Victoria · CA

Funding

Rapid 3D bioprinting of biomimetic vascularized tissue constructsR01EB021857 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, SHAOCHEN, DOKMECI, MEHMET REMZI · 2016 to 2019
$2.1M
Research Supplements to Promote DiversityR01GM126571 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOKMECI, MEHMET REMZI, YE, JING YONG · 2018 to 2021
$1.3M
NIBIB NIH HHS R01 EB021857NIGMS NIH HHS R01 GM126571
6 · The paper itself

Abstract

Patient deaths resulting from cardiovascular diseases are increasing across the globe, posing the greatest risk to patients in developed countries. Myocardial infarction, as a result of inadequate blood flow to the myocardium, results in irreversible loss of cardiomyocytes which can lead to heart failure. A sequela of myocardial infarction is scar formation that can alter the normal myocardial architecture and result in arrhythmias. Over the past decade, a myriad of tissue engineering approaches has been developed to fabricate engineered scaffolds for repairing cardiac tissue. This paper highlights the recent application of electrically conductive nanomaterials (carbon and gold-based nanomaterials, and electroactive polymers) to the development of scaffolds for cardiac tissue engineering. Moreover, this work summarizes the effects of these nanomaterials on cardiac cell behavior such as proliferation and migration, as well as cardiomyogenic differentiation in stem cells.

Indexed as

Electric ConductivityTissue EngineeringAnimalsBiocompatible MaterialsCarbonGoldHumansMyocardial InfarctionMyocytes, CardiacNanostructuresPolymersBiocompatible MaterialsCarbonGoldPolymersCarbon-based nanomaterialsCardiac tissue engineeringCardiovascular diseasesConductive nanomaterialsElectrically conductive scaffoldsElectroactive polymersGold nanoparticles

Identifiers

PMID31176755
PMCPMC6784829
OpenAlexW2949609590

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.