Evidence map›Paper›PMID 31176378›Full record

ArticleBMC pediatrics2019

Prevalence of vitamin D deficiency and its association with metabolic derangements among children with obesity.

S G S Adikaram, D B D L Samaranayake, N Atapattu, K M D L D Kendaragama, J T N Senevirathne, V Pujitha Wickramasinghe

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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  4. Vitamin D is glucoprotective in aging males but not females.The Journal of steroid biochemistry and molecular biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

S G S AdikaramColombo South Teaching Hospital, Kalubowila, Colombo, Sri Lanka.
D B D L SamaranayakeDepartment of Community Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
N AtapattuLady Ridgeway Hospital, Colombo, Sri Lanka.
K M D L D KendaragamaLady Ridgeway Hospital, Colombo, Sri Lanka.
J T N SenevirathneDepartment of Paediatrics, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, Sri Lanka.
V Pujitha WickramasingheDepartment of Paediatrics, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, Sri Lanka. pujithaw@yahoo.com.
University of Colombo · LKLady Ridgeway Hospital for Children · LKColombo North Teaching Hospital · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is known that obesity is associated with vitamin D deficiency and observational studies have shown vitamin D deficiency to be linked with the development of type 2 diabetes. There are no comprehensive data regarding vitamin D deficiency in children with obesity in Sri Lanka and the objective of the study was to assess the prevalence of Vitamin D deficiency and its association with metabolic derangements among children with obesity. METHODOLOGY: Two hundred and two children between 5 and 15 years of age attending the obesity clinic Lady Ridgeway Hospital (LRH) were recruited excluding those having possible secondary causes for obesity. Blood was drawn after 12-h overnight fast for fasting blood glucose(FBG), lipid profile, serum insulin, alanine aminotransferase (ALT),aspartate aminotransferase(AST), Vitamin D, parathyroid hormone(PTH),high sensitivity C reactive protein(hs-CRP). Oral glucose tolerance test (OGTT) was done with 2 h random blood glucose. Anthropometry, blood pressure were measured, and body fat mass was assessed using bio-impedance.

resultsVitamin D deficiency (< 20 ng/ml) was seen in 152(75.2%) children and 43(21.3%) had insufficient (20-30 ng/ml) levels. Skin fold thickness, fasting and post-glucose insulin, HOMA-IR, PTH, LDL, Serum cholesterol and hs-CRP showed statistically significant negative correlations with Vitamin D levels.

conclusionsVitamin D deficiency was significantly high in Sri Lankan children with obesity and showed significant negative correlations with indicators of insulin resistance and adiposity.

Indexed as

AdiposityAdolescentBlood GlucoseChildChild, PreschoolCholesterolCross-Sectional StudiesFemaleGlucose Tolerance TestHumansInsulinInsulin ResistanceIntra-Abdominal FatLipoproteins, HDLLiverMaleBlood GlucoseCholesterolInsulinLipoproteins, HDLTriglyceridesVitamin DChildhood obesitySri Lankan childrenVitamin D deficiency

Identifiers

PMID31176378
PMCPMC6555946
OpenAlexW2953582725

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.