Evidence map›Paper›PMID 31175519›Full record

ArticleJournal of muscle research and cell motility2019

Skeletal muscle fibre swelling contributes to force depression in rats and humans: a mechanically-skinned fibre study.

Daiki Watanabe, Travis L Dutka, Cedric R Lamboley, Graham D Lamb

Abstract read
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In one paragraph

Article in Journal of muscle research and cell motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. A combined experimental and computational analysis of mantATP turnover in skinned muscle fibers.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daiki WatanabeDepartment of Physiology Anatomy & Microbiology, La Trobe University, Melbourne, Australia. dwatanabe@hiroshima-u.ac.jp.
Travis L DutkaDepartment of Physiology Anatomy & Microbiology, La Trobe University, Melbourne, Australia.
Cedric R LamboleyDepartment of Physiology Anatomy & Microbiology, La Trobe University, Melbourne, Australia.
Graham D LambDepartment of Physiology Anatomy & Microbiology, La Trobe University, Melbourne, Australia.
La Trobe University · AUUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of fibre swelling on force production in rat and human skinned muscle fibres, using osmotic compression to reverse the fibre swelling. In mechanically-skinned fibres, the sarcolemma is removed but normal excitation-contraction coupling remains functional. Force responses in mechanically-skinned fibres were examined with and without osmotic compression by polyvinylpyrrolidone 40 kDa (PVP-40) or Dextran 500 kDa (dextran). Fibre diameter increased to 116 ± 2% (mean ± SEM) when rat skinned type II fibres were immersed in the standard intracellular solution, but remained close to the in situ size when 3% (mass/volume) PVP-40 or 4% Dextran were present. Myofibrillar Ca

Indexed as

AdultAnimalsDepressionHumansMaleMuscle FatigueMuscle Fibers, SkeletalRatsRats, Sprague-DawleyYoung AdultExcitation–contraction couplingMuscle swellingOsmolalitySkinned fibre

Identifiers

PMID31175519
OpenAlexW2956132575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.