Evidence map›Paper›PMID 31175434›Full record

ArticleJournal of neurology2019

Intra-arterial thrombectomy for acute ischaemic stroke patients with active cancer.

Dongwhane Lee, Deok Hee Lee, Dae Chul Suh, Hyuk Sung Kwon, Da-Eun Jeong, Joong-Goo Kim, Ji-Sung Lee, Jong S Kim, Dong-Wha Kang, Sang-Beom Jeon and 3 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

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  10. Long-term outcomes of mechanical thrombectomy in acute ischaemic stroke patients with concomitant malignancy.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Dongwhane LeeDepartment of Neurology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea.ORCID http://orcid.org/0000-0002-7795-6110
Deok Hee LeeDepartment of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Dae Chul SuhDepartment of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Hyuk Sung KwonDepartment of Neurology, Hanyang University College of Medicine, Seoul, South Korea.
Da-Eun JeongDepartment of Neurology, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, South Korea.
Joong-Goo KimDepartment of Neurology, Jeju National University Hospital, Jeju, South Korea.
Ji-Sung LeeClinical Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, South Korea.
Jong S KimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Dong-Wha KangDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Sang-Beom JeonDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Eun-Jae LeeDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kyung Chul NohDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Sun U KwonDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. sunkwon7@gmail.com.ORCID http://orcid.org/0000-0003-2247-3039
Ulsan College · KRAsan Medical Center · KRHanyang University · KRYeungnam University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThis study aimed to evaluate the efficacy of intra-arterial thrombectomy (IAT) and prognosis for acute ischaemic stroke patients with active cancer.

methodsWe retrospectively reviewed 253 patients who underwent IAT within 24 h after stroke onset between January 2012 and August 2017. We classified the patients into active cancer (n = 26) and control groups (n = 227) and compared clinical data. Primary outcome was a modified Rankin scale score at 3 months with ordinal logistic regression (shift analysis).

resultsInitial National Institutes of Health Stroke Scale (NIHSS) and rate of successful recanalisation did not differ between groups, but the active cancer group showed poor outcomes at 3 months on shift analysis (P = 0.001). The independent predictors of poor prognosis were age [adjusted common odds ratio (aOR) 1.03, 95% confidence interval (CI) 1.01-1.05], baseline NIHSS (aOR 1.14, 95% CI 1.09-1.19), baseline C-reactive protein level (aOR 1.14, 95% CI 1.03-1.25), any cerebral haemorrhage (aOR 1.92, 95% CI 1.21-3.06), and active cancer (aOR 2.35, 95% CI 1.05-5.25). Mortality at 90 days was 30.8% in the cancer group and 8.8% in the control group (P = 0.003).

conclusionsAlthough baseline characteristics and recanalisation rate after IAT up to 24 h after stroke onset were similar between acute ischaemic stroke patients with active cancer and without any cancer, stroke-related death and short-term outcome were significantly poorer in patients with active cancer than the controls. Post-procedural haemorrhage and active cancer itself were independent predictors of a decrease in functional independence at 3 months.

Indexed as

Cerebral ArteriesAgedAged, 80 and overBrain IschemiaFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasmsRetrospective StudiesStrokeThrombectomyCancer and strokeEndovascular recanalisationIschaemic strokeThrombectomy

Identifiers

PMID31175434
OpenAlexW2948319431

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.