Evidence map›Paper›PMID 31175391›Full record

SynthesisInternational journal of public health2019

Association between human papillomavirus and chlamydia trachomatis infection risk in women: a systematic review and meta-analysis.

Giulia Naldini, Chiara Grisci, Manuela Chiavarini, Roberto Fabiani

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  16. Expression of HPV-16 E6 and E7 oncoproteins altersFrontiers in cellular and infection microbiology · 2023
    Article
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  19. Sensitive and visual identification ofFrontiers in cellular and infection microbiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giulia NaldiniDepartment of Experimental Medicine, Section of Public Health, School of Specialization in Hygiene and Preventive Medicine, University of Perugia, Piazzale Gambuli, n.2, 06129, Perugia, Italy. giulia.naldini@studenti.unipg.it.ORCID http://orcid.org/0000-0002-3557-3015
Chiara GrisciDepartment of Experimental Medicine, Section of Public Health, School of Specialization in Hygiene and Preventive Medicine, University of Perugia, Piazzale Gambuli, n.2, 06129, Perugia, Italy.
Manuela ChiavariniDepartment of Experimental Medicine, Section of Public Health, University of Perugia, Perugia, Italy.
Roberto FabianiDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHuman papillomavirus (HPV) and chlamydia trachomatis (Ct) infection lead to severe consequences for women's health. This meta-analysis summarizes the evidence on HPV infection risk in women with chlamydia and chlamydia risk in HPV-positive women.

methodsMedline, Web of Science and Scopus were systematically searched for eligible publications until May 2018. Eligibility criteria included: assessment of HPV/Ct infection; cohort, case-control, cross-sectional study design; and reported risk estimation with its 95% CI for HPV infection in Ct-positive women and/or Ct infection in HPV-positive women. On the PRISMA guidelines, meta-analysis was performed using random effect model.

resultsForty-eight studies met the eligibility criteria. Among women with chlamydia, the odds ratio (OR) of HPV infection is 2.12 (95% CI 1.80, 2.49) and the OR of high-risk HPV infection is 2.32 (95% CI 2.02, 2.65). The OR for chlamydia among HPV-positive women is 2.23 (95% CI 1.70, 2.92).

conclusionsHPV and Ct behave as reciprocal risk factors. In women diagnosed with HPV infection or chlamydia, the screening for the mutual infection could represent a preventive intervention for severe reproductive health outcomes, such as cervical cancer and infertility.

Indexed as

ComorbidityAdultCase-Control StudiesChlamydia InfectionsChlamydia trachomatisCohort StudiesCross-Sectional StudiesFemaleHumansPapillomaviridaePapillomavirus InfectionsPrevalenceRisk FactorsSexually Transmitted DiseasesChlamydia trachomatisMeta-analysisPapillomavirus infectionsSexually transmitted diseasesSystematic reviewWomen’s health

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.