ArticleNature communications2019
Accounting for corner flow unifies the understanding of droplet formation in microfluidic channels.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- A Review on Micromixers, Microdroplet Generators and Their Integration.Micromachines · 2026Review
- Data-driven models for microfluidics: A short review.Biomicrofluidics · 2024Review
- Investigation of piezoelectric printing devices for oil-free and on-demand picolitre monodisperse droplet generation.Scientific reports · 2024Article
- Cost-Effective Droplet Generator for Portable Bio-Applications.Micromachines · 2023Article
- From dynamic self-organization to avalanching instabilities in soft-granular threads.Soft matter · 2022Article
- A portable droplet generation system for ultra-wide dynamic range digital PCR based on a vibrating sharp-tip capillary.Biosensors & bioelectronics · 2021Article
- Machine learning enables design automation of microfluidic flow-focusing droplet generation.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
While shear emulsification is a well understood industrial process, geometrical confinement in microfluidic systems introduces fascinating complexity, so far prohibiting complete understanding of droplet formation. The size of confined droplets is controlled by the ratio between shear and capillary forces when both are of the same order, in a regime known as jetting, while being surprisingly insensitive to this ratio when shear is orders of magnitude smaller than capillary forces, in a regime known as squeezing. Here, we reveal that further reduction of-already negligibly small-shear unexpectedly re-introduces the dependence of droplet size on shear/capillary-force ratio. For the first time we formally account for the flow around forming droplets, to predict and discover experimentally an additional regime-leaking. Our model predicts droplet size and characterizes the transitions from leaking into squeezing and from squeezing into jetting, unifying the description for confined droplet generation, and offering a practical guide for applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.