Evidence map›Paper›PMID 31175226›Full record

ArticleGenetics2019

Fibroblast Growth Factor Receptors Function Redundantly During Zebrafish Embryonic Development.

Dena M Leerberg, Rachel E Hopton, Bruce W Draper

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. The Influences of RARγ on the Behavior of Normal and Cancer Stem Cells.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Structure and function of the larval teleost fish gill.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
  9. Article
  10. Article
  11. A Potential Role ofDevelopment & reproduction · 2024
    Article
  12. Review
  13. Article
  14. Prognostic value ofContemporary oncology (Poznan, Poland) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dena M LeerbergDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616.ORCID 0000-0001-9731-998X
Rachel E HoptonDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616.
Bruce W DraperDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616 bwdraper@ucdavis.edu.ORCID 0000-0002-4397-7749
University of California, Davis · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Regulation of Vertebrate Gonad Formation by Fibroblast Growth Factor SignalingR01HD081551 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DRAPER, BRUCE W · 2015 to 2019
$1.6M
NCI NIH HHS P30 CA093373NICHD NIH HHS R01 HD081551NIGMS NIH HHS T32 GM007377
6 · The paper itself

Abstract

Fibroblast growth factor (Fgf) signaling regulates many processes during development. In most cases, one tissue layer secretes an Fgf ligand that binds and activates an Fgf receptor (Fgfr) expressed by a neighboring tissue. Although studies have identified the roles of specific Fgf ligands during development, less is known about the requirements for the receptors. We have generated null mutations in each of the five

Indexed as

Embryonic DevelopmentAnimalsBrainFibroblast Growth FactorsMesodermReceptors, Fibroblast Growth FactorZebrafishZebrafish Proteinsfgf8a protein, zebrafishFibroblast Growth FactorsReceptors, Fibroblast Growth FactorZebrafish ProteinsFibroblast growth factor signalingmidbrain-hindbrain boundaryneurocraniumpectoral finposterior mesodermviscerocranium

Identifiers

PMID31175226
PMCPMC6707458
OpenAlexW2967510247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.