Trial reportJournal of neuroengineering and rehabilitation2019
Walking to your right music: a randomized controlled trial on the novel use of treadmill plus music in Parkinson's disease.
Trial report in Journal of neuroengineering and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 68 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Music in Improving Gait Abnormalities in Parkinson Disease
A Randomized Trial on the Novel Use of Treadmill Plus Music in Multiple Sclerosis Patients With Gate Impairnent
Who cites it
68 citing papers in PubMed, 16 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- External sensory cueing on gait in Parkinson's disease: a systematic review and network meta-analysis.Journal of neurology · 2026Pooled it
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Art-based interventions and non-motor outcomes in Parkinson's disease: a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- The effectiveness of art therapy on motor function in Parkinson's disease: a systematic review and meta-analysis.Frontiers in psychology · 2025Pooled it
- Effectiveness and applications of neurologic music therapy in motor and non-motor rehabilitation for older adults with Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- The effects of nine types of exercise rehabilitation therapies on improving limb balance, cognitive and emotional function, and quality of life in elderly patients with Parkinson's disease: a network meta-analysis of 55 RCTs.Frontiers in neurology · 2025Pooled it
- Complementary therapies intervention in Parkinson's disease: systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effect of Music Based Therapy Rhythmic Auditory Stimulation (RAS) Using Wearable Device in Rehabilitation of Neurological Patients: A Systematic Review.Sensors (Basel, Switzerland) · 2023Pooled it
- Does Exercise Attenuate Disease Progression in People With Parkinson's Disease? A Systematic Review With Meta-Analyses.Neurorehabilitation and neural repair · 2023Pooled it
- Effects of Music-Based Interventions on Motor and Non-Motor Symptoms in Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Interventions for preventing falls in Parkinson's disease.The Cochrane database of systematic reviews · 2022Pooled it
- Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline From the American Physical Therapy Association.Physical therapy · 2022Guideline
- Effects of Rhythmic Auditory Stimulation on Gait and Motor Function in Parkinson's Disease: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Studies.Frontiers in neurology · 2022Pooled it
- Chronic effects of different exercise types on brain activity in healthy older adults and those with Parkinson's disease: A systematic review.Frontiers in physiology · 2022Pooled it
- Rhythmic auditory stimulation promotes gait recovery in Parkinson's patients: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Music Therapy and Parkinson's Disease: A Systematic Review from 2015-2020.International journal of environmental research and public health · 2021Pooled it
- Music and Exercise in Concert: Uncovering Synergistic Mechanisms for Enhancing Brain Health and Cognitive Resilience-A Narrative Review.Brain and behavior · 2026Review
- A Digital Cueing Intervention for Parkinsonian Gait: Laboratory-Based Clinical Validation and Acute Gait Responses.Journal of medical systems · 2026Article
- Auditory contributions to postural and locomotor control: from basic research to clinical applications.Experimental brain research · 2026Review
- Potential Effects of Music on Non-Motor Symptoms in Parkinson's Disease: Translating Mechanisms to Therapy.Neurology international · 2026Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRhythmic Auditory Stimulation (RAS) can compensate for the loss of automatic and rhythmic movements in patients with idiopathic Parkinson's disease (PD). However, the neurophysiological mechanisms underlying the effects of RAS are still poorly understood. We aimed at identifying which mechanisms sustain gait improvement in a cohort of patients with PD who practiced RAS gait training.
methodsWe enrolled 50 patients with PD who were randomly assigned to two different modalities of treadmill gait training using GaitTrainer3 with and without RAS (non_RAS) during an 8-week training program. We measured clinical, kinematic, and electrophysiological effects of both the gait trainings.
resultsWe found a greater improvement in Functional Gait Assessment (p < 0.001), Tinetti Falls Efficacy Scale (p < 0.001), Unified Parkinson Disease Rating Scale (p = 0.001), and overall gait quality index (p < 0.001) following RAS than non_RAS training. In addition, the RAS gait training induced a stronger EEG power increase within the sensorimotor rhythms related to specific periods of the gait cycle, and a greater improvement of fronto-centroparietal/temporal electrode connectivity than the non_RAS gait training.
conclusionsThe findings of our study suggest that the usefulness of cueing strategies during gait training consists of a reshape of sensorimotor rhythms and fronto-centroparietal/temporal connectivity. Restoring the internal timing mechanisms that generate and control motor rhythmicity, thus improving gait performance, likely depends on a contribution of the cerebellum. Finally, identifying these mechanisms is crucial to create patient-tailored, RAS-based rehabilitative approaches in PD.
trial registrationNCT03434496 . Registered 15 February 2018, retrospectively registered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.