ArticleEnvironmental health and preventive medicine2019
Associations between metal concentrations in whole blood and placenta previa and placenta accreta: the Japan Environment and Children's Study (JECS).
Article in Environmental health and preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maternal Smoking and the Risk of Placenta Accreta Spectrum: A Systematic Review and Meta-Analysis.BioMed research international · 2022Pooled it
- The effects of developmental cadmium exposure on health and disease.Disease models & mechanisms · 2025Review
- Placenta Praevia with Abnormal Adhesion-A Retrospective Study.Clinics and practice · 2025Article
- Association between maternal heavy metal exposure and Kawasaki Disease, the Japan Environment and Children's Study (JECS).Scientific reports · 2024Article
- Emergency Obstetric Hysterectomy after Conservative Management of Placenta Accreta.Case reports in obstetrics and gynecology · 2023Article
- Association between maternal fish consumption during pregnancy and preterm births: the Japan Environment and Children's Study.Environmental health and preventive medicine · 2023Article
- Clinical Analysis of Factors Influencing the Development of Placenta Praevia and Perinatal Outcomes in First-Time Pregnant Patients.Frontiers in surgery · 2022Article
- Association between the Concentrations of Metallic Elements in Maternal Blood during Pregnancy and Prevalence of Abdominal Congenital Malformations: The Japan Environment and Children's Study.International journal of environmental research and public health · 2021Article
- Effect of types of placenta previa on maternal and neonatal outcomes: a 10-year retrospective cohort study.Archives of gynecology and obstetrics · 2021Article
- Effect of previous placenta previa on outcome of next pregnancy: a 10-year retrospective cohort study.BMC pregnancy and childbirth · 2020Article
- Oral exposure to lead for Japanese children and pregnant women, estimated using duplicate food portions and house dust analyses.Environmental health and preventive medicine · 2019Article
- Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats.Environmental health and preventive medicine · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlacenta previa and placenta accreta associate with high morbidity and mortality for both mothers and fetus. Metal exposure may have relationships with placenta previa and placenta accreta. This study analyzed the associations between maternal metal (cadmium [Cd], lead [Pb], mercury [Hg], selenium [Se], and manganese [Mn]) concentrations and placenta previa and placenta accreta.
methodsWe recruited 17,414 women with singleton pregnancies. Data from a self-administered questionnaire regarding the first trimester and medical records after delivery were analyzed. Maternal blood samples were collected to measure metal concentrations. The subjects were classified into four quartiles (Q1, Q2, Q3, and Q4) according to metal concentrations.
resultsThe odds ratio for placenta previa was significantly higher among subjects with Q4 Cd than those with Q1 Cd. The odds ratio for placenta previa was significantly higher for subjects with Q2 Pb than those with Q1 Pb.
conclusionParticipants with placenta previa had higher Cd concentrations. However, this study was cross-sectional and lacked important information related to Cd concentration, such as detailed smoking habits and sources of Cd intake. In addition, the subjects in this study comprised ordinary pregnant Japanese women, and it was impossible to observe the relationship between a wide range of Cd exposure and placenta previa. Therefore, epidemiological and experimental studies are warranted to verify the relationship between Cd exposure and pregnancy abnormalities.
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