Evidence map›Paper›PMID 31174267›Full record

ArticleJournal of clinical medicine2019

Usefulness of the Thrombotic Microangiopathy Score as a Promising Prognostic Marker of Septic Shock for Patients in the Emergency Department.

Dong Ryul Ko, Taeyoung Kong, Hye Sun Lee, Sinae Kim, Jong Wook Lee, Hyun Soo Chung, Sung Phil Chung, Je Sung You, Jong Woo Park

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dong Ryul KoDepartment of Emergency Medicine, Yonsei University College of Medicine, 06273 Seoul, Korea. kkdry@yuhs.ac.ORCID 0000-0002-3098-2784
Taeyoung KongDepartment of Emergency Medicine, Yonsei University College of Medicine, 06273 Seoul, Korea. grampian@yuhs.ac.ORCID 0000-0002-4182-7245
Hye Sun LeeDepartment of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, 06273 Seoul, Korea. HSLEE1@yuhs.ac.ORCID 0000-0001-6328-6948
Sinae KimDepartment of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, 06273 Seoul, Korea. ksn1214@yuhs.ac.
Jong Wook LeeDepartment of Laboratory Medicine, Konyang University Hospital, 35365 Daejon, Korea. lee423619@kyuh.ac.kr.
Hyun Soo ChungDepartment of Emergency Medicine, Yonsei University College of Medicine, 06273 Seoul, Korea. HSC104@yuhs.ac.
Sung Phil ChungDepartment of Emergency Medicine, Yonsei University College of Medicine, 06273 Seoul, Korea. emstar@yuhs.ac.
Je Sung YouDepartment of Emergency Medicine, Yonsei University College of Medicine, 06273 Seoul, Korea. youjsmd@yuhs.ac.
Jong Woo ParkDepartment of Emergency Medicine, Good Sunlin Hospital, 37725 Pohang, Korea. erman@daum.net.

Funding

National Research Foundation of Korea 2018R1C1B6006159
6 · The paper itself

Abstract

The thrombotic microangiopathy (TMA) score based on the development and morphological characteristics of schistocytes is a rapid, simple biomarker that is easily obtained from the complete blood cell count by an automated blood cell analyzer. We aimed to determine whether the TMA score is associated with 30-day mortality of patients with early-stage septic shock. This observational cohort study was retrospectively conducted based on a prospective emergency department (ED) registry (June 2015-December 2016). We analyzed the TMA score at ED admission and 24 h later. The primary endpoint was all-cause mortality within 30 days of ED admission. A total of 221 patients were included. Increased TMA scores at time 0 (odds ratio (OR), 1.972; 95% confidence interval (CI), 1.253-3.106;

Indexed as

mortalitypredictorsepsisthrombotic microangiopathy score

Identifiers

PMID31174267
PMCPMC6617054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.