ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2020
Gaps in Viral Hepatitis Awareness in the United States in a Population-based Study.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Prevalence of Latent Tuberculosis Infection Among Persons with Chronic Hepatitis B Virus Infection: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2022Pooled it
- Health Within Reach-a Patient-Centered Intervention to Increase Hepatitis B Screening Among Asian Americans: a Randomized Clinical Trial.Journal of general internal medicine · 2022Trial
- Exploring the Psychosocial Influences on Hepatitis B and Liver Cancer Disparities.Journal of racial and ethnic health disparities · 2026Article
- Chronic Viral Hepatitis Screening Inequities Across Florida Federally Qualified Health Centers.Journal of racial and ethnic health disparities · 2026Article
- Low awareness of viral causes of Cancer among United States adults by smoking status: findings from health information national trends survey (2024).Preventive medicine reports · 2026Article
- Immigration Factors and Monitoring of Chronic Hepatitis B Infection Among Foreign-Born: The FOCUS-HBV Multicentre Cohort.Alimentary pharmacology & therapeutics · 2025Article
- Liver Cancer Etiology in Asian Subgroups and American Indian, Black, Latino, and White Populations.JAMA network open · 2025Article
- Article
- Contemporary awareness of viral hepatitis between 2012 and 2022 among Korean adults.Clinical and molecular hepatology · 2025Article
- Gaps and disparities in the treatment of chronic hepatitis B infection in the USA.Gastroenterology report · 2025Review
- Identifying barriers to hepatitis B and delta screening, prevention, and linkage to care among people who use drugs in Philadelphia, Pennsylvania, USA.Harm reduction journal · 2024Article
- Hepatitis B Virus Infection in Eastern Libya: Current Efforts for Overcoming Regional Barriers for Its Elimination.Journal of community health · 2024Article
- The Challenge of a Recall Program from a Community-Based Hepatitis C Screening Campaign: The Effectiveness in HCV Microelimination.Microorganisms · 2024Article
- What Hepatitis C Virus (HCV) Diagnostic Tools Are Needed to Advance Diagnosis of Current HCV Infection in Outreach Settings and in a Nonclinical Setting?The Journal of infectious diseases · 2024Article
- Down-Classification of Hepatitis C Virus Diagnostics: Implications for Screening and Diagnosis.The Journal of infectious diseases · 2024Article
- Awareness and infection prevention practices of hepatitis B virus among informal caregivers in public hospitals of Addis Ababa, Ethiopia, 2024.Frontiers in epidemiology · 2024Article
- Country-Specific Screening, Prevalence, and Immunity Rates for Hepatitis B Infection in a Large US Safety-Net System.Open forum infectious diseases · 2024Article
- Impact of HCV Testing and Treatment on HCV Transmission Among Men Who Have Sex With Men and Who Inject Drugs in San Francisco: A Modelling Analysis.The Journal of infectious diseases · 2023Article
- Knowledge and awareness of viral hepatitis and influencing factors among the general population aged 15-69 years in Zhejiang Province, China.Human vaccines & immunotherapeutics · 2023Article
- Racial Disparities in Treatment Initiation and Outcomes of Chronic Hepatitis B Virus Infection in North America.JAMA network open · 2023Observational
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsThe benefits of highly effective therapies for chronic hepatitis B virus (HBV) or HCV infection can only be realized if infected individuals are identified and linked to care. We sought to identify gaps in awareness of diagnosis of HBV or HCV infection in a population-based sample of adults living in the United States (US).
methodsUsing National Health and Nutrition Examinations Surveys data, we examined factors associated with HBV and HCV awareness. Participants surveyed from 2013 through 2016, age ≥20 years, with complete serologic analyses were included. HBV and HCV infections were defined by detection of serum HBsAg and anti-HCV, respectively. The primary outcome was awareness of infection-if participants replied "yes" to the question: "Has a doctor or other health professional ever told you that you have hepatitis B or C?"
resultsOf 14,745 participants, 68 had HBV and 211 had HCV infection, corresponding to prevalence values of 0.7% and 1.8%, respectively. Among HBV-infected persons, 32% reported awareness, and 28% of aware persons reported treatment. Among HCV-infected persons, 49% reported awareness, 45% of aware persons were treated, and 59% of treated patients achieved a sustained virologic response. Factors associated with greater awareness in multivariable models included US citizenship, higher education, and abnormal level of alanine aminotransferase for HBV-infected participants and non-Hispanic race, income above the poverty line, not married, and history of injection drug use for HCV-infected participants.
conclusionsFewer than half of US adults with HBV or HCV infection are aware of their infection. Opportunities to increase awareness include provider education on cut-off values for abnormal level of alanine aminotransferase that should prompt screening, and expansion of existing screening interventions to under-recognized at-risk groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.