Evidence map›Paper›PMID 31173534›Full record

ArticleJournal of dental research2019

Mutant Dentin Sialophosphoprotein Causes Dentinogenesis Imperfecta.

T Liang, H Zhang, Q Xu, S Wang, C Qin, Y Lu

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Functions of secretory calcium-binding phosphoproteins in dental mineralization.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Dentin defects caused by a DsppScientific reports · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

T Liang1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.
H Zhang1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.
Q Xu1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.
S Wang1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.
C Qin1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.
Y Lu1 Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA.ORCID 0000-0003-3692-1736
Texas A&M University · US

Funding

The Roles of FAM20C (DMP4) in Odontogenesis and OsteogenesisR01DE022549 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI QIN, CHUNLIN · 2013 to 2017
$1.8M
Dentin Sialophosphoprotein (DSPP) and Unfolded Protein Response (UPR) in Dentinogenesis Imperfecta (DGI) and Odontoblast FunctionR01DE027345 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LU, YONGBO, QIN, CHUNLIN · 2018 to 2022
$1.8M
Identification and Function of nuDMP1 in Odontoblast DifferentiationR01DE023365 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LU, YONGBO · 2013 to 2016
$1.3M
NIDCR NIH HHS R01 DE022549NIDCR NIH HHS R01 DE023365NIDCR NIH HHS R01 DE027345
6 · The paper itself

Abstract

Dentin sialophosphoprotein (DSPP) is an extracellular matrix protein highly expressed by odontoblasts in teeth. DSPP mutations in humans may cause dentinogenesis imperfecta (DGI), an autosomal dominant dentin disorder. We recently generated a mouse model (named "

Indexed as

AnimalsDentinDentinogenesisDentinogenesis ImperfectaDentin SialophosphoproteinDisease Models, AnimalExtracellular Matrix ProteinsHumansMiceOdontoblastsPhosphoproteinsSialoglycoproteinsDentin SialophosphoproteinExtracellular Matrix ProteinsPhosphoproteinsSialoglycoproteinsextracellular matrixgeneticsmineralized tissue/developmentodontoblast(s)odontogenesistooth development

Identifiers

PMID31173534
PMCPMC6616118
OpenAlexW2958071455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.