ArticleArchives of pathology & laboratory medicine2019
Implementation of Digital Pathology Offers Clinical and Operational Increase in Efficiency and Cost Savings.
Article in Archives of pathology & laboratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Digital pathology in forensic science: a systematic review of the literature.Forensic science, medicine, and pathology · 2026Pooled it
- Technical and Diagnostic Issues in Whole Slide Imaging Published Validation Studies.Frontiers in oncology · 2022Pooled it
- Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide.The Journal of pathology · 2026Review
- Whole-slide imaging in hematopathology: Current state, challenges and future opportunities.Journal of pathology informatics · 2026Review
- Evaluating the Performance of LYDIA: An AI-Powered Assistant in the Detection of Metastatic Tumors to Optimize Clinical Workflows and Inform Soft Tissue Surgical Decision-Making.Bioengineering (Basel, Switzerland) · 2026Article
- Accelerating the implementation of digital pathology in India.Journal of pathology informatics · 2026Review
- Application and exploration of digital pathology technology in standardized residency training.BMC medical education · 2026Article
- Diagnostic challenges of faded hematoxylin and eosin slides: limitations of re-staining and re-sectioning and possible reason to go digital.Virchows Archiv : an international journal of pathology · 2026Article
- Digital Pathology in Hematopathology: From Vision to Deployment.International journal of laboratory hematology · 2026Review
- Telepathology Development and Stakeholder Perspectives in China: Cross-Sectional Survey.JMIR medical informatics · 2026Article
- Applications and challenges of utilizing digital pathology and AI-enabled workflows in clinical trials.Journal of pathology informatics · 2026Review
- Artificial intelligence in genitourinary pathology.Histopathology · 2026Review
- Deployment of Artificial Intelligence in Clinical Oral Pathology: Evidence Summary and Implementation Gaps.Analytical cellular pathology (Amsterdam) · 2026Review
- Bridging the digital pathology divide: reciprocal learning between high-resource and low-resource settings.BMJ digital health & AI · 2026Review
- HER2 testing results, practices, and preferences among pathologists and oncologists in the US community setting: a mixed-methods study.Breast cancer research and treatment · 2025Article
- Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Digital pathology enabling lean management of HER2/neu testing in breast Cancer.Journal of pathology informatics · 2025Article
- Implementing digital pathology: qualitative and financial insights from eight leading European laboratories.Virchows Archiv : an international journal of pathology · 2025Article
- From Microscopes to Monitors: Unique Opportunities and Challenges in Digital Pathology Implementation in Remote Canadian Regions.Diagnostics (Basel, Switzerland) · 2025Article
- GPU-Accelerated Artificial Intelligence Applications in Cancer Diagnosis, Imaging, and Treatment Planning.Asian Pacific journal of cancer prevention : APJCP · 2025Review
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
CONTEXT.—: Digital pathology (DP) implementations vary in scale, based on aims of intended operation. Few laboratories have completed a full-scale DP implementation, which may be due to high overhead costs that disrupt the traditional pathology workflow. Neither standardized criteria nor benchmark data have yet been published showing practical return on investment after implementing a DP platform. OBJECTIVE.—: To provide benchmark data and practical metrics to support operational efficiency and cost savings in a large academic center. DESIGN.—: Metrics reviewed include archived pathology asset retrieval; ancillary test request for recurrent/metastatic disease; cost analysis and turnaround time (TAT); and DP experience survey. RESULTS.—: Glass slide requests from the department slide archive and an off-site surgery center showed a 93% and 97% decrease, respectively. Ancillary immunohistochemical orders, compared in 2014 (52%)-before whole slide images (WSIs) were available in the laboratory information system-and 2017 (21%) showed $114 000/y in anticipated savings. Comprehensive comparative cost analysis showed a 5-year $1.3 million savings. Surgical resection cases with prior WSIs showed a 1-day decrease in TAT. A DP experience survey showed 80% of respondents agreed WSIs improved their clinical sign-out experience. CONCLUSIONS.—: Implementing a DP operation showed a noteworthy increase in efficiency and operational utility. Digital pathology deployments and operations may be gauged by the following metrics: number of glass slide requests as WSIs become available, decrease in confirmatory testing for patients with metastatic/recurrent disease, long-term decrease in off-site pathology asset costs, and faster TAT. Other departments may use our benchmark data and metrics to enhance patient care and demonstrate return on investment to justify adoption of DP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.