Evidence map›Paper›PMID 31173119›Full record

SynthesisJAMA network open2019

Association of Communication Interventions to Discuss Code Status With Patient Decisions for Do-Not-Resuscitate Orders: A Systematic Review and Meta-analysis.

Christoph Becker, Leopold Lecheler, Seraina Hochstrasser, Kerstin A Metzger, Madlaina Widmer, Emanuel B Thommen, Katharina Nienhaus, Hannah Ewald, Christoph A Meier, Florian Rueter and 3 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in JAMA network open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Article
  6. A Team Approach to Patient-Centered Communication in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
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  19. Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes.Circulation. Cardiovascular quality and outcomes · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Christoph BeckerDepartment of Emergency Medicine, University Hospital Basel, Basel, Switzerland.
Leopold LechelerMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Seraina HochstrasserMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Kerstin A MetzgerMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Madlaina WidmerMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Emanuel B ThommenMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Katharina NienhausMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Hannah EwaldBasel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Christoph A MeierClinic for Internal Medicine, University Hospital Basel, Basel, Switzerland.
Florian RueterQuality Management, University Hospital Basel, Basel, Switzerland.
Rainer SchaefertMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Stefano BassettiClinic for Internal Medicine, University Hospital Basel, Basel, Switzerland.
Sabina HunzikerMedical Communication, Department of Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Whether specific communication interventions to discuss code status alter patient decisions regarding do-not-resuscitate code status and knowledge about cardiopulmonary resuscitation (CPR) remains unclear. Objective: To conduct a systematic review and meta-analysis regarding the association of communication interventions with patient decisions and knowledge about CPR. Data Sources: PubMed, Embase, PsycINFO, and CINAHL were systematically searched from the inception of each database to November 19, 2018. Study Selection: Randomized clinical trials focusing on interventions to facilitate code status discussions. Two independent reviewers performed the data extraction and assessed risk of bias using the Cochrane Risk of Bias Tool. Data were pooled using a fixed-effects model, and risk ratios (RRs) with corresponding 95% CIs are reported. Data Extraction and Synthesis: The study was performed according to the PRISMA guidelines. Main Outcomes and Measures: The primary outcome was patient preference for CPR, and the key secondary outcome was patient knowledge regarding life-sustaining treatment. Results: Fifteen randomized clinical trials (2405 patients) were included in the qualitative synthesis, 11 trials (1463 patients) were included for the quantitative synthesis of the primary end point, and 5 trials (652 patients) were included for the secondary end point. Communication interventions were significantly associated with a lower preference for CPR (390 of 727 [53.6%] vs 284 of 736 [38.6%]; RR, 0.70; 95% CI, 0.63-0.78). In a preplanned subgroup analysis, studies using resuscitation videos as decision aids compared with other interventions showed a stronger decrease in preference for life-sustaining treatment (RR, 0.56; 95% CI, 0.48-0.64 vs 1.03; 95% CI, 0.87-1.22; between-group heterogeneity P < .001). Also, a significant association was found between communication interventions and better patient knowledge (standardized mean difference, 0.55; 95% CI, 0.39-0.71). Conclusions and Relevance: Communication interventions are associated with patient decisions regarding do-not-resuscitate code status and better patient knowledge and may thus improve code status discussions.

Indexed as

CommunicationDecision MakingPatient PreferenceAdvance DirectivesCardiopulmonary ResuscitationHealth Knowledge, Attitudes, PracticeHumansResuscitation Orders

Identifiers

PMID31173119
PMCPMC6563579

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.