ArticleJournal of experimental botany2019
CEP3 levels affect starvation-related growth responses of the primary root.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Integrated Gene Regulatory Network Analysis Reveals Coordinated Transcriptional Reprogramming in thePlants (Basel, Switzerland) · 2026Article
- CEPR1 function across plant lineages: peptide hormone recognition by cereal crop orthologs and developmental roles in barley.Journal of experimental botany · 2025Article
- Promiscuity and specificity in ligand sensing by plant cell surface receptors.PLoS pathogens · 2025Article
- The TaCEP15 peptide signaling cascade modulates primary root length and drought tolerance in wheat.Science advances · 2025Article
- CEPR2 perceives group II CEPs to regulate cell surface receptor-mediated immunity in Arabidopsis.PLoS pathogens · 2025Article
- Decoding Long-Distance Communication Under Mineral Stress: Advances in Vascular Signalling and Molecular Tools for Plant Resilience.Plant, cell & environment · 2025Review
- CEP signaling coordinates plant immunity with nitrogen status.Nature communications · 2024Article
- CEP hormones at the nexus of nutrient acquisition and allocation, root development, and plant-microbe interactions.Journal of experimental botany · 2024Review
- Root-Knot-Nematode-Encoded CEPs Increase Nitrogen Assimilation.Life (Basel, Switzerland) · 2023Article
- Metabolic regulation of quiescence in plants.The Plant journal : for cell and molecular biology · 2023Article
- CEP peptide and cytokinin pathways converge on CEPD glutaredoxins to inhibit root growth.Nature communications · 2023Article
- Control of the rhizobium-legume symbiosis by the plant nitrogen demand is tightly integrated at the whole plant level and requires inter-organ systemic signaling.Frontiers in plant science · 2023Review
- Functional characterization of C-TERMINALLY ENCODED PEPTIDE (CEP) family inPlant signaling & behavior · 2022Article
- Identification and Expression Analysis of theInternational journal of molecular sciences · 2022Article
- Systematic Annotation RevealsCells · 2022Article
- Progress in the Self-Regulation System in Legume Nodule Development-AON (Autoregulation of Nodulation).International journal of molecular sciences · 2022Review
- At the Root of Nodule Organogenesis: Conserved Regulatory Pathways Recruited by Rhizobia.Plants (Basel, Switzerland) · 2021Review
- Multigene editing reveals that MtCEP1/2/12 redundantly control lateral root and nodule number in Medicago truncatula.Journal of experimental botany · 2021Article
- Signaling Peptides Regulating Abiotic Stress Responses in Plants.Frontiers in plant science · 2021Review
- The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium inMolecular & cellular proteomics : MCP · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CEPs (C-TERMINALLY ENCODED PEPTIDEs) inhibit Arabidopsis primary root growth by unknown mechanisms. We investigated how CEP3 levels control primary root growth. CEP3 peptide application decreased cell division, S-phase cell number, root meristematic cell number, and meristem zone (MZ) size in a dose- and CEP RECEPTOR1-dependent manner. Grafting showed that CEP3-dependent growth inhibition requires root and shoot CEPR1. CEP3 induced mitotic quiescence in MZ cells significantly faster than that induced by nutrient limitation alone. CEP3 also inhibited the restoration of S-phase to mitotically quiescence cells by nutrient resupply without quantitatively reducing TARGET OF RAPAMYCIN (TOR) kinase activity. In contrast, cep3-1 had an increased meristem size and S-phase cell number under nitrogen (N)-limited conditions, but not under N-sufficient conditions. Furthermore, cep3-1 meristematic cells remained in S-phase longer than wild-type cells during a sustained carbon (C) and N limitation. RNA sequencing showed that CEP3 peptide down-regulated genes involved in S-phase entry, cell wall and ribosome biogenesis, DNA replication, and meristem expansion, and up-regulated genes involved in catabolic processes and proteins and peptides that negatively control meristem expansion and root growth. Many of these genes were reciprocally regulated in cep3-1. The results suggest that raising CEP3 induces starvation-related responses that curtail primary root growth under severe nutrient limitation.
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