ArticleJournal of medical Internet research2019
Accelerating Health Data Sharing: A Solution Based on the Internet of Things and Distributed Ledger Technologies.
Article in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Blockchain technology in healthcare: A systematic review.PloS one · 2022Pooled it
- Blockchain Integration With Digital Technology and the Future of Health Care Ecosystems: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Blockchain Technology Projects to Provide Telemedical Services: Systematic Review.Journal of medical Internet research · 2021Pooled it
- The Current State of Research, Challenges, and Future Research Directions of Blockchain Technology in Patient Care: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Patient-governed agentic health data exchange.npj health systems · 2026Review
- Blockchain Technology in Digital Health and Medical Technologies.Blockchain in healthcare today · 2025Article
- ICT in Nursing and Patient Healthcare Management: Scoping Review and Case Studies.Sensors (Basel, Switzerland) · 2024Article
- PUFchain 3.0: Hardware-Assisted Distributed Ledger for Robust Authentication in Healthcare Cyber-Physical Systems.Sensors (Basel, Switzerland) · 2024Article
- Article
- Designing a Private and Secure Personal Health Records Access Management System: A Solution Based on IOTA Distributed Ledger Technology.Sensors (Basel, Switzerland) · 2023Article
- Comprehensive review for healthcare data quality challenges in blockchain technology.Frontiers in big data · 2023Review
- Hurdles to developing and scaling remote patients' health management tools and systems: a scoping review.Systematic reviews · 2022Article
- Exploring the COVID-19 Pandemic as a Catalyst for Behavior Change Among Patient Health Record App Users in Taiwan: Development and Usability Study.Journal of medical Internet research · 2022Article
- Design and implementation of hybrid consensus mechanism for IoT based healthcare system security.International journal of information technology : an official journal of Bharati Vidyapeeth's Institute of Computer Applications and Management · 2022Article
- Information Technology Ambidexterity, Digital Dynamic Capability, and Knowledge Processes as Enablers of Patient Agility: Empirical Study.JMIRx med · 2021Article
- Integration of Artificial Intelligence, Blockchain, and Wearable Technology for Chronic Disease Management: A New Paradigm in Smart Healthcare.Current medical science · 2021Article
- The perspectives of biomarker-based electrochemical immunosensors, artificial intelligence and the Internet of Medical Things toward COVID-19 diagnosis and management.Materials today. Chemistry · 2021Review
- Consumers' Intentions to Adopt Blockchain-Based Personal Health Records and Data Sharing: Focus Group Study.JMIR formative research · 2020Article
- Combating Health Care Fraud and Abuse: Conceptualization and Prototyping Study of a Blockchain Antifraud Framework.Journal of medical Internet research · 2020Article
- Approaches Based on Artificial Intelligence and the Internet of Intelligent Things to Prevent the Spread of COVID-19: Scoping Review.Journal of medical Internet research · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuge amounts of health-related data are generated every moment with the rapid development of Internet of Things (IoT) and wearable technologies. These big health data contain great value and can bring benefit to all stakeholders in the health care ecosystem. Currently, most of these data are siloed and fragmented in different health care systems or public and private databases. It prevents the fulfillment of intelligent health care inspired by these big data. Security and privacy concerns and the lack of ensured authenticity trails of data bring even more obstacles to health data sharing. With a decentralized and consensus-driven nature, distributed ledger technologies (DLTs) provide reliable solutions such as blockchain, Ethereum, and IOTA Tangle to facilitate the health care data sharing.
objectiveThis study aimed to develop a health-related data sharing system by integrating IoT and DLT to enable secure, fee-less, tamper-resistant, highly-scalable, and granularly-controllable health data exchange, as well as build a prototype and conduct experiments to verify the feasibility of the proposed solution.
methodsThe health-related data are generated by 2 types of IoT devices: wearable devices and stationary air quality sensors. The data sharing mechanism is enabled by IOTA's distributed ledger, the Tangle, which is a directed acyclic graph. Masked Authenticated Messaging (MAM) is adopted to facilitate data communications among different parties. Merkle Hash Tree is used for data encryption and verification.
resultsA prototype system was built according to the proposed solution. It uses a smartwatch and multiple air sensors as the sensing layer; a smartphone and a single-board computer (Raspberry Pi) as the gateway; and a local server for data publishing. The prototype was applied to the remote diagnosis of tremor disease. The results proved that the solution could enable costless data integrity and flexible access management during data sharing.
conclusionsDLT integrated with IoT technologies could greatly improve the health-related data sharing. The proposed solution based on IOTA Tangle and MAM could overcome many challenges faced by other traditional blockchain-based solutions in terms of cost, efficiency, scalability, and flexibility in data access management. This study also showed the possibility of fully decentralized health data sharing by replacing the local server with edge computing devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.