Evidence map›Paper›PMID 31172945›Full record

ArticleeLife2019

Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization.

Kalyn Kono, Shigeki Yoshiura, Ikumi Fujita, Yasushi Okada, Atsunori Shitamukai, Tatsuo Shibata, Fumio Matsuzaki

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Liquid-liquid phase separation in neural development.Cellular and molecular life sciences : CMLS · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Roles of Par3, Par6, and aPKC Polarity Proteins in Normal Neurodevelopment and in Neurodegenerative and Neuropsychiatric Disorders.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kalyn KonoLaboratory of Molecular Cell Biology and Development, Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.ORCID 0000-0002-1558-7153
Shigeki Yoshiura *Laboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Ikumi Fujita *Laboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0002-1161-0352
Yasushi OkadaLaboratory for Cell Polarity Regulation, RIKEN Center for Biosystems Dynamics Research, Osaka, Japan.ORCID 0000-0003-2601-3689
Atsunori ShitamukaiLaboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0003-4216-927X
Tatsuo ShibataLaboratory for Physical Biology, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0002-9294-9998
Fumio MatsuzakiLaboratory of Molecular Cell Biology and Development, Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.ORCID 0000-0001-7902-4520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular polarization is fundamental for various biological processes. The Par network system is conserved for cellular polarization. Its core complex consists of Par3, Par6, and aPKC. However, the general dynamic processes that occur during polarization are not well understood. Here, we reconstructed Par-dependent polarity using non-polarized

Indexed as

Cell PolarityDrosophilaAnimalsCell LineDrosophila ProteinsIntracellular Signaling Peptides and ProteinsProtein Kinase Cbaz protein, DrosophilaDrosophila ProteinsIntracellular Signaling Peptides and ProteinsPar-6 protein, DrosophilaProtein Kinase Ccell biologycell polarityPar complexphase separationreconstructionsuper resolution microscopysynthetic biology

Identifiers

PMID31172945
PMCPMC6555595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.