Evidence map›Paper›PMID 31172914›Full record

ReviewMicrobiology spectrum2019

Clostridial Genetics: Genetic Manipulation of the Pathogenic Clostridia.

S A Kuehne, J I Rood, D Lyras

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Oncology research · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Make It LessGenes · 2022
    Review
  8. CRISPR-Cas9-Based Toolkit forFrontiers in microbiology · 2021
    Article
  9. Nanaerobic growth enables direct visualization of dynamic cellular processes in human gut symbionts.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

S A KuehneSchool of Dentistry and Institute for Microbiology and Infection, University of Birmingham, Birmingham, UK.
J I RoodInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia 3800.
D LyrasInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia 3800.
Australian Regenerative Medicine Institute · AUMonash University · AUUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past 10 years have been revolutionary for clostridial genetics. The rise of next-generation sequencing led to the availability of annotated whole-genome sequences of the important pathogenic clostridia:

Indexed as

Clostridioides difficileClostridiumClostridium botulinumClostridium perfringensClustered Regularly Interspaced Short Palindromic RepeatsGene DeletionGene Expression Regulation, BacterialGenetic EngineeringGenome, BacterialMutagenesisMutation

Identifiers

PMID31172914
PMCPMC11315012
OpenAlexW2943947586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.