Evidence map›Paper›PMID 31172697›Full record

ArticleJournal of Korean medical science2019

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.

Kyung Bok Lee, Jung Gon Lee, Beom Joon Kim, Jun Yup Kim, Keon Joo Lee, Moon Ku Han, Jong Moo Park, Kyusik Kang, Yong Jin Cho, Hong Kyun Park and 21 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Body Composition Alterations in Patients with Chronic Stroke: A Cross-Sectional Study.Journal of musculoskeletal & neuronal interactions · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Change in Bone Mineral Density in Stroke Patients with Osteoporosis or Osteopenia.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Article
  9. Observational
  10. Factors associated with fracture after stroke and TIA: a long-term follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 12 institutions in 1 country.

Kyung Bok LeeDepartment of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2663-7483
Jung Gon LeeDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-3093-996X
Beom Joon KimDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0002-2719-3012
Jun Yup KimDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-4764-5714
Keon Joo LeeDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0002-6571-7091
Moon Ku HanDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0166-387X
Jong Moo ParkDepartment of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.ORCID https://orcid.org/0000-0002-4199-3024
Kyusik KangDepartment of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.ORCID https://orcid.org/0000-0002-4021-4439
Yong Jin ChoDepartment of Neurology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.ORCID https://orcid.org/0000-0002-7843-1148
Hong Kyun ParkDepartment of Neurology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.ORCID https://orcid.org/0000-0002-8120-2469
Keun Sik HongDepartment of Neurology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.ORCID https://orcid.org/0000-0002-4684-6111
Tai Hwan ParkDepartment of Neurology, Seoul Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-5148-1663
Soo Joo LeeDepartment of Neurology, Daejeon Eulji Medical Center, Eulji University, Daejeon, Korea.ORCID https://orcid.org/0000-0001-8622-7000
Mi Sun OhDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.ORCID https://orcid.org/0000-0002-6741-0464
Kyung Ho YuDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.ORCID https://orcid.org/0000-0002-8997-5626
Byung Chul LeeDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.ORCID https://orcid.org/0000-0002-3885-981X
Jae Kwan ChaDepartment of Neurology, Dong-A University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0002-1049-5196
Dae Hyun KimDepartment of Neurology, Dong-A University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0003-4716-9551
Joon Tae KimDepartment of Neurology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0002-4116-4832
Jun LeeDepartment of Neurology, Yeungnam University Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0001-7829-7105
Jeong Ho HongDepartment of Neurology, Keimyung University Dongsan Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-8235-9855
Sung Il SohnDepartment of Neurology, Keimyung University Dongsan Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-6900-1242
Dong Eog KimDepartment of Neurology, Dongguk University Ilsan Hopital, Goyang, Korea.ORCID https://orcid.org/0000-0002-9339-6539
Jay Chol ChoiDepartment of Neurology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.ORCID https://orcid.org/0000-0002-3550-2196
Min Ju YeoDepartment of Neurology, Chungbuk National University Hospital, Cheongju, Korea.ORCID https://orcid.org/0000-0003-0871-6030
Wook Joo KimDepartment of Neurology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0001-5290-0623
Jae Eun ChaeDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9069-0575
Ji Sung LeeClinical Research Center, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8194-3462
Juneyoung LeeDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8073-9304
Hee Joon BaeDepartment of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. braindoc@snu.ac.kr.ORCID https://orcid.org/0000-0003-0051-1997
CRCS-K investigators
Korea University · KRSeoul National University Bundang Hospital · KRDong-A University Hospital · KREulji University · KRHallym University Sacred Heart Hospital · KRInje University Ilsan Paik Hospital · KRKeimyung University Dongsan Medical Center · KRSoonchunhyang University Hospital Seoul · KRChungbuk National University Hospital · KRJeju National University Hospital · KRSeoul Medical Center · KRUlsan University Hospital · KR

Funding

Korea Centers for Disease Control & Prevention 2017ER620101Soonchunhyang University
6 · The paper itself

Abstract

backgroundPatients who survive an acute phase of stroke are at risk of falls and fractures afterwards. However, it is largely unknown how frequent fractures occur in the Asian stroke population.

methodsPatients with acute (< 7 days) ischemic stroke who were hospitalized between January 2011 and November 2013 were identified from a prospective multicenter stroke registry in Korea, and were linked to the National Health Insurance Service claim database. The incidences of fractures were investigated during the first 4 years after index stroke. The cumulative incidence functions (CIFs) were estimated by the Gray's test for competing risk data. Fine and Gray model for competing risk data was applied for exploring risk factors of post-stroke fractures.

resultsAmong a total of 11,522 patients, 1,616 fracture events were identified: 712 spine fractures, 397 hip fractures and 714 other fractures. The CIFs of any fractures were 2.63% at 6 months, 4.43% at 1 year, 8.09% at 2 years and 13.00% at 4 years. Those of spine/hip fractures were 1.11%/0.61%, 1.88%/1.03%, 3.28%/1.86% and 5.79%/3.15%, respectively. Age by a 10-year increment (hazard ratio [HR], 1.23; 95% confidence interval [CI], 1.17-1.30), women (HR, 1.74; 95% CI, 1.54-1.97), previous fracture (HR, 1.72; 95% CI, 1.54-1.92) and osteoporosis (HR, 1.44; 95% CI, 1.27-1.63) were independent risk factors of post-stroke fracture.

conclusionThe CIFs of fractures are about 8% at 2 years and 13% at 4 years after acute ischemic stroke in Korea. Older age, women, pre-stroke fracture and osteoporosis raised the risk of post-stroke fractures.

Indexed as

AgedAged, 80 and overDatabases, FactualFemaleFractures, BoneHip FracturesHumansIncidenceMaleMiddle AgedOsteoporosisProportional Hazards ModelsRepublic of KoreaRisk FactorsStrokeFractureIncidenceStroke

Identifiers

PMID31172697
PMCPMC6556443
OpenAlexW2947003621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.