ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2019
Cortical morphometry in anorexia nervosa: An out-of-sample replication study.
Article in European eating disorders review : the journal of the Eating Disorders Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07098156 (Neuroanatomical Differences Associated With Anorexia Nervosa and Masking Behaviour in Autistic Individuals), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neuroanatomical Differences Associated With Anorexia Nervosa and Masking Behaviour in Autistic Individuals
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Cortical complexity in eating disorders: a systematic review and qualitative synthesis.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group.Biological psychiatry · 2022Pooled it
- A meta-analytic investigation of grey matter differences in anorexia nervosa and autism spectrum disorder.European eating disorders review : the journal of the Eating Disorders Association · 2022Pooled it
- Eating and Mental Health Disorders.Nutrients · 2026Article
- Neural correlates of children with avoidant restrictive food intake disorder symptoms: large-scale neuroanatomical analysis of a paediatric population.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Neuroanatomical associations with autistic characteristics in those with acute anorexia nervosa and weight-restored individuals.Psychological medicine · 2025Article
- Mendelian randomization analyses support causal relationships between systemic lupus erythematosus and brain imaging-derived phenotypes.Frontiers in neurology · 2024Article
- Examining the relationship between autistic spectrum disorder characteristics and structural brain differences seen in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2022Article
- Cortical Gyrification Morphology in Adult Males with Mild Traumatic Brain Injury.Neurotrauma reports · 2022Article
- Volumetric Alterations of the Cerebral Cortex in Eating Disorders.Journal of clinical medicine · 2021Article
- Altered functional connectivity in adolescent anorexia nervosa is related to age and cortical thickness.BMC psychiatry · 2021Article
- Structural brain differences in recovering and weight-recovered adult outpatient women with anorexia nervosa.Journal of eating disorders · 2021Article
- Cortical Gyrification in Transgender Individuals.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Cortical thinning and associated connectivity changes in patients with anorexia nervosa.Translational psychiatry · 2021Article
- Cortical morphometry in anorexia nervosa: An out-of-sample replication study.European eating disorders review : the journal of the Eating Disorders Association · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAcute anorexia nervosa (AN) is frequently accompanied by reduced global cortical volume. Investigations of local cortical alterations in AN have revealed widespread reduction in cortical thickness, gyrification, and curvature. The aim of the present study was to combine data from two previous studies to replicate previous findings. METHODOLOGY: Magnetic resonance imaging (MRI) images from 46 adult women with AN and 54 age-matched healthy comparison (HC) women were analysed using FreeSurfer. Group differences in cortical volume and local cortical measures, including gyrification, curvature, thickness, and area, were examined controlling for dataset and age.
resultsThe AN group had reduced global cortical volume relative to the HC group. The AN group also had reduction in local cortical gyrification, small localised clusters of reduced cortical thickness, in the occipital and parietal cortices, and surface area in the frontal and temporal cortices. The AN group also had increased cortical thickness in the ACC relative to the HC participants.
conclusionsThe present findings replicate and validate previous findings of reduced global cortical volume and local gyrification in acute AN. The findings highlight the need for further investigation of local cortical folding, thickness, and surface area in AN to gain further insight into the biological underpinnings of AN.
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