Evidence map›Paper›PMID 31172462›Full record

ArticleOphthalmology and therapy2019

Electron Beam Irradiated Corneal Versus Gamma-Irradiated Scleral Patch Graft Erosion Rates in Glaucoma Drainage Device Surgery.

Ross M Passo, Zachary B Hoskins, Khoa D Tran, Corrina Patzer, Beth Edmunds, John C Morrison, Mansi Parikh, Hana L Takusagawa, Shandiz Tehrani

Open access · goldAbstract read
In one paragraph

Article in Ophthalmology and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ross M PassoDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA. rosspasso@gmail.com.
Zachary B HoskinsDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Khoa D TranLions VisionGift, Portland, OR, USA.
Corrina PatzerLions VisionGift, Portland, OR, USA.
Beth EdmundsDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
John C MorrisonDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Mansi ParikhDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Hana L TakusagawaDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Shandiz TehraniDepartment of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Oregon Health & Science University · USMinnesota Lions Eye Bank · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
NEI NIH HHS P30 EY010572NEI NIH HHS P30EY010572
6 · The paper itself

Abstract

introductionPatch graft erosion and implant exposure is a known complication of glaucoma drainage device (GDD) surgery. Recently, electron beam (e-beam) irradiated corneal tissue ha s become available; however, limited data exist on the rates of erosion for e-beam irradiated corneal grafts compared to traditional scleral grafts after GDD surgery.

methodsThis retrospective study examines the records of 253 eyes from 225 adult subjects who underwent GDD surgery with either e-beam irradiated corneal or scleral grafts at the Casey Eye Institute by five surgeons between April 22, 2014 and October 11, 2017. Surgical procedures and the occurrence of graft erosion were determined using billing codes and verified by manual review of electronic health records.

resultsThe average age at the time of surgery was 61.3 ± 17.5 years (n = 200) and 60.8 ± 16.8 years (n = 53) for the e-beam irradiated cornea and sclera groups, respectively. The average follow-up time post-surgery was 416 ± 345 days and 495 ± 343 days for the e-beam irradiated cornea and sclera groups, respectively. There were no statistically significant differences in sex, age, follow-up time, and glaucoma diagnosis between the groups; however, the e-beam irradiated cornea group was statistically more likely to have an Ahmed implant as compared to the sclera group. No erosion events were noted in either group.

conclusione-Beam irradiated corneal grafts were used 3.8 times more frequently relative to scleral grafts, yet there were no cases of graft erosion in either group during the follow-up period.

Indexed as

Corneal patch graftGlaucoma drainage device (GDD)Graft erosionScleral patch graftTube exposure

Identifiers

PMID31172462
PMCPMC6692416
OpenAlexW2955165956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.