Evidence map›Paper›PMID 31172280›Full record

ArticleWorld journal of urology2020

Intra- and inter-resting-state networks abnormalities in overactive bladder syndrome patients: an independent component analysis of resting-state fMRI.

Long Zuo, Jingnan Chen, Shuangkun Wang, Yang Zhou, Biao Wang, Hua Gu

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05989646 (Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children, and Modulation of Brain Activity by Transcutaneous Electrical Nerve Stimulation - a Functional Magnetic Resonance Imaging Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05989646 narecruitingnot on this mapstarted 2021, after this paper: background citation

Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children, and Modulation of Brain Activity by Transcutaneous Electrical Nerve Stimulation - a Functional Magnetic Resonance Imaging Study

TypeinterventionalSponsorAalborg University HospitalRan2021 to 2027Enrolled65ConditionsUrinary Incontinence, Daytime Wetting, Urination Disorders, Urination InvoluntaryArmsSacral TENS
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Long ZuoDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Jingnan ChenSchool of Economics and Management, Beihang University, Beijing, China.
Shuangkun WangDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China. shuangkunwang@126.com.ORCID http://orcid.org/0000-0002-2389-6765
Yang ZhouDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Biao WangDepartment of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Hua GuDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.

Funding

Beihang University Research Fund Program under Project ZG216S1871National Natural Science Foundation of China 81541129National Natural Science Foundation of China () 81301016National Natural Science Foundation of China () KZ73100001
6 · The paper itself

Abstract

purposeThis study aims to determine whether intra-network and inter-network brain connectivities are altered using an independent component analysis (ICA).

methodsResting-state functional MRI (rs-fMRI) data were acquired from 26 patients with OAB and 28 healthy controls (HC). Eleven resting-state networks (RSNs) were identified via ICA. General linear model (GLM) was used to compare intra-network FC and inter-network FC of RSNs between the two groups. Pearson correlation analyses were performed to investigate the relationship between the identified RSNs and clinical variables.

resultsCompared with HC, the OAB group showed abnormal FC within the sensorimotor-related network (SMN), the dorsal attention network (DAN), the dorsal visual network (dVN), and the left frontoparietal network (LFPN). With respect to inter-network interactions, decreased FC was detected between the SMN and the anterior default mode network (aDMN).

conclusionThis study demonstrated that abnormal FC between RSNs may reflect the altered resting state of the brain-bladder network. The findings of this study provide complementary evidence that can help further understand the neural substrates of the overactive bladder.

Indexed as

Magnetic Resonance ImagingAdultBrainCross-Sectional StudiesFemaleHumansMaleMiddle AgedNerve NetSyndromeUrinary Bladder, OveractiveFunctional magnetic resonanceIndependent component analysisOveractive bladder syndrome

Identifiers

PMID31172280

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.