Evidence map›Paper›PMID 31172212›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2019

Lesion detection by [

Sarah R Verhoeff, Suzanne C van Es, Eline Boon, Erik van Helden, Lindsay Angus, Sjoerd G Elias, Sjoukje F Oosting, Erik H Aarntzen, Adrienne H Brouwers, Thomas C Kwee and 9 more

Open access · hybridAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Prospective pilot study with [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Pharmaceutics · 2026
    Article
  11. Review
  12. Review
  13. Potential Clinical Applications of HyperpolarizedRecent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  14. Carbonic Anhydrase Inhibitors in Oncology.Sub-cellular biochemistry · 2026
    Review
  15. Article
  16. Isoechoic Renal Tumors: A Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 2 countries.

Sarah R VerhoeffDepartment of Medical Oncology, Radboud University Medical Center Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Suzanne C van EsDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Eline BoonDepartment of Medical Oncology, Radboud University Medical Center Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Erik van HeldenDepartment of Medical Oncology, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Lindsay AngusDepartments of Medical Oncology and Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Sjoerd G EliasDepartment of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Sjoukje F OostingDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Erik H AarntzenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Adrienne H BrouwersDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Thomas C KweeDepartment of Radiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Sandra HeskampDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Otto S HoekstraDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Henk VerheulDepartment of Medical Oncology, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Astrid A M van der VeldtDepartments of Medical Oncology and Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Elisabeth G E de VriesDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Otto C BoermanDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Winette T A van der GraafDepartment of Medical Oncology, Radboud University Medical Center Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Wim J G OyenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Carla M L van HerpenDepartment of Medical Oncology, Radboud University Medical Center Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Carla.vanherpen@radboudumc.nl.
Radboud University Medical Center · NLRadboud University Nijmegen · NLUniversity of Groningen · NLErasmus MC · NLUniversity Medical Center Groningen · NLAcademic Medical Center · NLCancer Center AmsterdamRijnstate Hospital · NLUniversity Medical Center Utrecht · NLVrije Universiteit Amsterdam · NL

Funding

KWF Kankerbestrijding 2012-5400
6 · The paper itself

Abstract

purposeThe main objective of this preliminary analysis of the IMaging PAtients for Cancer drug selecTion (IMPACT)-renal cell cancer (RCC) study is to evaluate the lesion detection of baseline contrast-enhanced CT, [

methodsBetween February 2015 and March 2018, 42 newly diagnosed mccRCC patients with good or intermediate prognosis, eligible for watchful waiting, were included. Patients underwent CT, [

resultsA total of 449 lesions were detected by ≥1 modality (median per patient: 7; ICR 4.25-12.75) of which 42% were in lung, 22% in lymph nodes and 10% in bone. Combined [

conclusionsThe addition of [

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyAdultAgedAged, 80 and overAntibodies, MonoclonalBiological TransportCarcinoma, Renal CellCohort StudiesDeferoxamineFemaleHumansKidney NeoplasmsMaleMiddle AgedNeoplasm Metastasis(89)Zr-girentuximabAntibodies, MonoclonalDeferoxamineFluorodeoxyglucose F18CAIXClear cell renal cell carcinomaFDGGirentuximabImagingPET

Identifiers

PMID31172212
PMCPMC6647180
OpenAlexW2948579877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.