ArticleEye and vision (London, England)2019
Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus.
Article in Eye and vision (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04160338 (A Specular Microscopic Study of Corneal Endothelium After Accelerated Corneal Collagen Cross Linking), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Specular Microscopic Study of Corneal Endothelium After Accelerated Corneal Collagen Cross Linking
Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Comparison of accelerated corneal collagen cross-linking under normal and increased oxygen concentrations: A pilot study.Indian journal of ophthalmology · 2026Trial
- The efficiency and safety of oxygen-supplemented accelerated transepithelial corneal cross-linking.International ophthalmology · 2021Trial
- The Science and Clinical Evolution of Corneal Cross-Linking: Mechanism of Action, Ultra-Structural Changes, Clinical Indications, and Emerging Treatment Strategies.Ophthalmology and therapy · 2026Review
- Effects of customized corneal cross-linking on higher-order aberrations in progressive keratoconus and low-grade myopia.Acta ophthalmologica · 2025Article
- Evaluation of photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) in feline infectious keratitis-patient demographics, treatment protocols, risk factors, and treatment outcome: a retrospective study.Veterinary ophthalmology · 2025Article
- Effect of accelerated high-fluence riboflavin and rose bengal-mediated corneal cross-linking on resistance to enzymatic digestion.BMC ophthalmology · 2024Article
- Topography-guided photorefractive keratectomy combined with accelerated corneal collagen cross-linking versus cross-linking alone for progressive keratoconus: a long-term prospective cohort study.Frontiers in medicine · 2024Article
- The effect of accelerated pulsed high-fluence corneal cross-linking on corneal endothelium; a prospective specular microscopy study.BMC ophthalmology · 2023Article
- Commentary: Bunsen-Roscoe reciprocity - Is it still valid?Indian journal of ophthalmology · 2022Article
- Corneal higher-order aberration changes after accelerated cross-linking for keratoconus.BMC ophthalmology · 2022Article
- Chemically-Boosted Corneal Cross-Linking for the Treatment of Keratoconus through a Riboflavin 0.25% Optimized Solution with High Superoxide Anion Release.Journal of clinical medicine · 2021Article
- Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases.Frontiers in pharmacology · 2021Review
- Factors Affecting Visual Gain after Accelerated Crosslinking in Pediatric Keratoconic Cases.Beyoglu eye journal · 2021Article
- Complications of accelerated corneal collagen cross-linking: review of 2025 eyes.International ophthalmology · 2020Article
- Comparison of Two Different Accelerated Corneal Cross-linking Procedure Outcomes in Patients with KeratoconusBalkan medical journal · 2020Article
- Comparative Results of "Epi-Off" Conventional versus "Epi-Off" Accelerated Cross-Linking Procedure at 5-year Follow-Up.Journal of ophthalmology · 2020Article
- Accelerated Epithelium-Off Corneal Collagen Cross-Linking For Keratoconus: 12-Month Results.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- A Novel Oxygen Chamber for Corneal Cross-Linking in a High-Oxygen Environment: A Pilot Study and Clinical Outcomes.Journal of current ophthalmologyArticle
- Accelerated versus Standard Corneal Cross-linking for Progressive Keratoconus in Syria.Journal of ophthalmic & vision researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare the outcomes of two different protocols of accelerated corneal crosslinking (CXL) on visual, corneal high order aberrations (HOA) and topographic parameters in patients with progressive keratoconus.
methodsIn this prospective comparative study, sixty-six eyes of 66 patients with progressive keratoconus were divided into two groups; 37 eyes in Group 1 received 18 mW/cm
resultsThe mean UCVA and BCVA were significantly improved at the postoperative 12 months compared with the preoperative values in both groups (P < 0.05 for all). A significant improvement in corneal HOAs was observed in both groups (P < 0.05 for all). The change in corneal coma value was significantly higher in Group 2 (P < 0.05). The change in keratometric values K1, K2, AvgK and maximum keratometry (AKf) were significantly higher in Group 2 (P < 0.05 for all). The regression model showed that the most important factor predicting the change in AKf was the type of CXL (β = - 0.482,
conclusionsAccelerated CXL using 10 min of UVA irradiance at 9 mW/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.