Evidence map›Paper›PMID 31171791›Full record

ArticleNature communications2019

Introducing risk inequality metrics in tuberculosis policy development.

M Gabriela M Gomes, Juliane F Oliveira, Adelmo Bertolde, Diepreye Ayabina, Tuan Anh Nguyen, Ethel L Maciel, Raquel Duarte, Binh Hoa Nguyen, Priya B Shete, Christian Lienhardt

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M Gabriela M GomesLiverpool School of Tropical Medicine, Liverpool, L3 5QA, United Kingdom. gabriela.gomes@lstmed.ac.uk.ORCID http://orcid.org/0000-0002-1454-4979
Juliane F OliveiraCIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, 4485-661, Portugal.ORCID http://orcid.org/0000-0002-7167-8754
Adelmo BertoldeDepartamento de Estatística, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, 29075-910, Brazil.
Diepreye AyabinaLiverpool School of Tropical Medicine, Liverpool, L3 5QA, United Kingdom.
Tuan Anh NguyenNational Lung Hospital, Hanoi, 10000, Vietnam.
Ethel L MacielLaboratório de Epidemiologia, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, 29047-105, Brazil.
Raquel DuarteFaculdade de Medicina, and EPIUnit, Instituto de Saúde Pública, Universidade do Porto, Porto, 4050-091, Portugal.
Binh Hoa NguyenNational Lung Hospital, Hanoi, 10000, Vietnam.
Priya B SheteDivision of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, CA, 94110, USA.
Christian LienhardtGlobal TB Programme, World Health Organization, 1211 Geneva 27, Geneva, Switzerland.

Funding

Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation) OPP1131404World Health Organization 001
6 · The paper itself

Abstract

Global stakeholders including the World Health Organization rely on predictive models for developing strategies and setting targets for tuberculosis care and control programs. Failure to account for variation in individual risk leads to substantial biases that impair data interpretation and policy decisions. Anticipated impediments to estimating heterogeneity for each parameter are discouraging despite considerable technical progress in recent years. Here we identify acquisition of infection as the single process where heterogeneity most fundamentally impacts model outputs, due to selection imposed by dynamic forces of infection. We introduce concrete metrics of risk inequality, demonstrate their utility in mathematical models, and pack the information into a risk inequality coefficient (RIC) which can be calculated and reported by national tuberculosis programs for use in policy development and modeling.

Indexed as

Health PolicyRiskBrazilHealth Status DisparitiesHumansModels, TheoreticalPolicy MakingPortugalRisk AssessmentTuberculosisVietnamWorld Health Organization

Identifiers

PMID31171791
PMCPMC6554307

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.