Evidence map›Paper›PMID 31171721›Full record

ArticleThe Journal of biological chemistry2019

Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival.

Jeanine C Pestoni, Stephani Klingeman Plati, Oliver D Valdivia Camacho, Marisa A Fuse, Maria Onatunde, Nicklaus A Sparrow, Matthias A Karajannis, Cristina Fernández-Valle, Maria Clara Franco

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Nitration in cancer signaling.Redox biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jeanine C PestoniDepartment of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, Oregon 97331.
Stephani Klingeman PlatiBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827.
Oliver D Valdivia CamachoDepartment of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, Oregon 97331.
Marisa A FuseBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827.
Maria OnatundeBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827.
Nicklaus A SparrowBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827.
Matthias A KarajannisDepartment of Pediatrics and Otolaryngology, NYU Langone Health, New York, New York 10016.
Cristina Fernández-ValleBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827.
Maria Clara FrancoDepartment of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, Oregon 97331 maria.franco@oregonstate.edu.ORCID 0000-0002-7971-9805
University of Central Florida · USOregon State University · USNYU Langone Health · US

Funding

Redox Signaling in NeurofibromatosisR01NS102479 · NINDS · OREGON STATE UNIVERSITY · PI FRANCO, MARIA CLARA · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS102479
6 · The paper itself

Abstract

Neurofibromatosis type 2 (NF2) is an autosomal-dominant disorder characterized by the development of bilateral vestibular schwannomas. The

Indexed as

Genes, Tumor SuppressorAnimalsCells, CulturedCell SurvivalGlutamineGlycolysisHumansMiceMitochondriaNeurofibromatosis 2Oxidative PhosphorylationOxygen ConsumptionPeroxynitrous AcidSchwann CellsGlutaminePeroxynitrous Acidbioenergeticsenergy metabolismmerlinneurofibromatosisnitrationperoxynitriteredox signalingSchwann cellsschwannomatumor metabolism

Identifiers

PMID31171721
PMCPMC6663865
OpenAlexW2964484378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.