Evidence map›Paper›PMID 31171718›Full record

ArticleThe Journal of biological chemistry2019

Spermidine strongly increases the fidelity of

Pierre Plateau, Clara Moch, Sylvain Blanquet

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Ultrasensitive CRISPR/Cas12a-Based System for Detection ofCurrent issues in molecular biology · 2025
    Article
  2. Review
  3. Functional polyamine metabolic enzymes and pathways encoded by the virosphere.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Polyamines and linear DNA mediate bacterial threat assessment of bacteriophage infection.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pierre PlateauBIOC, CNRS, Ecole polytechnique, IP Paris, F-91128 Palaiseau, France pierre.plateau@polytechnique.edu.
Clara MochBIOC, CNRS, Ecole polytechnique, IP Paris, F-91128 Palaiseau, France.
Sylvain BlanquetBIOC, CNRS, Ecole polytechnique, IP Paris, F-91128 Palaiseau, France.
École Polytechnique · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Site-selective CRISPR array expansion at the origin of bacterial adaptive immunity relies on recognition of sequence-dependent DNA structures by the conserved Cas1-Cas2 integrase. Off-target integration of a new spacer sequence outside canonical CRISPR arrays has been described

Indexed as

CRISPR-Cas SystemsBinding SitesDNA, BacterialDNA, SuperhelicalEscherichia coliEscherichia coli ProteinsIntegrasesIntegration Host FactorsSpermidineDNA, BacterialDNA, SuperhelicalEscherichia coli ProteinsIntegrasesIntegration Host FactorsSpermidineCRISPR/CasDNA-protein interactiongenomic instabilityintegraseintegration host factor (IHF)polyamine

Identifiers

PMID31171718
PMCPMC6643042
OpenAlexW2963816039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.